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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL21
All Species:
18.18
Human Site:
S181
Identified Species:
66.67
UniProt:
Q9UKT6
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKT6
NP_036291.2
434
49152
S181
F
I
N
S
K
S
L
S
S
I
K
I
E
D
T
Chimpanzee
Pan troglodytes
XP_527020
434
49071
S181
F
I
N
S
K
S
L
S
S
I
K
I
E
D
T
Rhesus Macaque
Macaca mulatta
XP_001110935
434
49077
S181
F
I
N
S
K
S
L
S
S
I
K
I
E
D
T
Dog
Lupus familis
XP_542618
428
48669
K178
S
K
S
L
S
S
L
K
I
D
D
T
P
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFZ4
434
49135
S181
F
V
N
S
K
S
L
S
S
I
K
I
E
D
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512543
456
51777
S203
F
V
N
S
K
S
L
S
S
L
K
I
D
D
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120533
320
36053
F102
Q
L
L
R
I
K
G
F
P
R
L
L
P
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
93
70.7
N.A.
85.9
N.A.
N.A.
68.1
N.A.
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
N.A.
Protein Similarity:
100
97.4
95.3
84.3
N.A.
92.4
N.A.
N.A.
81.1
N.A.
N.A.
N.A.
N.A.
N.A.
44
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
93.3
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
15
15
0
15
72
15
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
58
15
0
% E
% Phe:
72
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
43
0
0
15
0
0
0
15
58
0
72
0
0
0
% I
% Lys:
0
15
0
0
72
15
0
15
0
0
72
0
0
0
0
% K
% Leu:
0
15
15
15
0
0
86
0
0
15
15
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
15
0
0
0
29
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
15
0
0
0
0
0
15
0
0
0
0
0
% R
% Ser:
15
0
15
72
15
86
0
72
72
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
72
% T
% Val:
0
29
0
0
0
0
0
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _