KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW2
All Species:
14.85
Human Site:
S143
Identified Species:
29.7
UniProt:
Q9UKT8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKT8
NP_036296.2
454
51512
S143
H
E
A
F
E
T
S
S
L
I
G
H
S
A
R
Chimpanzee
Pan troglodytes
XP_001157864
486
55209
S175
H
E
A
F
E
T
S
S
L
I
G
H
S
A
R
Rhesus Macaque
Macaca mulatta
XP_001096076
455
51692
S143
H
E
A
F
E
T
S
S
L
I
G
H
S
A
R
Dog
Lupus familis
XP_867821
389
44448
S92
K
Q
W
N
K
V
I
S
A
C
T
E
V
W
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60584
422
47892
K125
H
W
K
K
V
Y
L
K
A
I
L
R
M
K
Q
Rat
Rattus norvegicus
B2RZ17
454
51389
S143
H
E
A
F
E
T
S
S
L
I
G
H
S
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PTR5
410
46646
R113
G
H
R
S
P
V
T
R
V
I
F
H
P
V
F
Frog
Xenopus laevis
Q91854
518
59489
G189
F
K
N
K
P
P
D
G
K
T
P
P
N
S
F
Zebra Danio
Brachydanio rerio
Q7T394
410
46494
R113
G
H
R
S
P
V
T
R
V
I
F
H
P
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203222
435
49086
W138
T
V
Y
Q
K
A
L
W
R
L
K
Q
L
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39014
640
72817
R337
F
T
G
K
L
I
R
R
L
S
G
H
S
D
G
Red Bread Mold
Neurospora crassa
Q01277
650
72171
V289
N
S
R
Y
K
L
S
V
L
K
G
H
E
N
G
Conservation
Percent
Protein Identity:
100
93.4
95.5
85.6
N.A.
90.7
98.6
N.A.
N.A.
22
20.2
21.5
N.A.
N.A.
N.A.
N.A.
47.8
Protein Similarity:
100
93.4
97.3
85.6
N.A.
91.8
99.5
N.A.
N.A.
39.2
36.8
38.5
N.A.
N.A.
N.A.
N.A.
66.7
P-Site Identity:
100
100
100
6.6
N.A.
13.3
100
N.A.
N.A.
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
20
100
N.A.
N.A.
26.6
20
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.9
20.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
0
0
9
0
0
17
0
0
0
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
9
% D
% Glu:
0
34
0
0
34
0
0
0
0
0
0
9
9
0
0
% E
% Phe:
17
0
0
34
0
0
0
0
0
0
17
0
0
0
25
% F
% Gly:
17
0
9
0
0
0
0
9
0
0
50
0
0
0
17
% G
% His:
42
17
0
0
0
0
0
0
0
0
0
67
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
59
0
0
0
0
0
% I
% Lys:
9
9
9
25
25
0
0
9
9
9
9
0
0
9
0
% K
% Leu:
0
0
0
0
9
9
17
0
50
9
9
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
0
9
9
0
0
0
0
0
0
0
0
9
9
0
% N
% Pro:
0
0
0
0
25
9
0
0
0
0
9
9
17
0
0
% P
% Gln:
0
9
0
9
0
0
0
0
0
0
0
9
0
0
17
% Q
% Arg:
0
0
25
0
0
0
9
25
9
0
0
9
0
9
34
% R
% Ser:
0
9
0
17
0
0
42
42
0
9
0
0
42
9
0
% S
% Thr:
9
9
0
0
0
34
17
0
0
9
9
0
0
0
0
% T
% Val:
0
9
0
0
9
25
0
9
17
0
0
0
9
17
0
% V
% Trp:
0
9
9
0
0
0
0
9
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
9
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _