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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW2
All Species:
15.15
Human Site:
S319
Identified Species:
30.3
UniProt:
Q9UKT8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKT8
NP_036296.2
454
51512
S319
C
K
C
L
K
T
L
S
V
S
E
D
R
S
I
Chimpanzee
Pan troglodytes
XP_001157864
486
55209
S351
C
K
C
L
K
T
L
S
V
S
E
D
R
S
I
Rhesus Macaque
Macaca mulatta
XP_001096076
455
51692
S320
C
K
C
L
K
T
L
S
V
S
E
D
R
S
I
Dog
Lupus familis
XP_867821
389
44448
P265
D
R
S
I
C
L
Q
P
R
L
H
F
D
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60584
422
47892
K298
Y
I
L
L
S
A
D
K
Y
E
I
K
I
W
P
Rat
Rattus norvegicus
B2RZ17
454
51389
S319
C
K
C
L
K
T
L
S
V
S
E
D
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PTR5
410
46646
P286
V
E
C
I
S
W
A
P
E
S
S
Y
S
T
I
Frog
Xenopus laevis
Q91854
518
59489
K378
A
S
G
D
R
T
I
K
V
W
N
T
S
T
C
Zebra Danio
Brachydanio rerio
Q7T394
410
46494
P286
V
E
C
I
S
W
A
P
E
S
A
H
P
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203222
435
49086
I311
L
S
M
D
K
S
I
I
K
V
W
P
I
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39014
640
72817
T513
T
P
S
N
E
Q
E
T
V
L
D
E
N
I
P
Red Bread Mold
Neurospora crassa
Q01277
650
72171
L462
V
G
H
V
Q
Q
V
L
I
L
P
P
E
Y
E
Conservation
Percent
Protein Identity:
100
93.4
95.5
85.6
N.A.
90.7
98.6
N.A.
N.A.
22
20.2
21.5
N.A.
N.A.
N.A.
N.A.
47.8
Protein Similarity:
100
93.4
97.3
85.6
N.A.
91.8
99.5
N.A.
N.A.
39.2
36.8
38.5
N.A.
N.A.
N.A.
N.A.
66.7
P-Site Identity:
100
100
100
0
N.A.
6.6
100
N.A.
N.A.
20
13.3
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
100
N.A.
N.A.
40
33.3
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.9
20.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
17
0
0
0
9
0
0
0
0
% A
% Cys:
34
0
50
0
9
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
0
0
17
0
0
9
0
0
0
9
34
9
0
0
% D
% Glu:
0
17
0
0
9
0
9
0
17
9
34
9
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
0
9
0
25
0
0
17
9
9
0
9
0
17
9
50
% I
% Lys:
0
34
0
0
42
0
0
17
9
0
0
9
0
0
9
% K
% Leu:
9
0
9
42
0
9
34
9
0
25
0
0
0
0
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
9
0
9
0
0
% N
% Pro:
0
9
0
0
0
0
0
25
0
0
9
17
9
0
17
% P
% Gln:
0
0
0
0
9
17
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
9
0
0
0
9
0
0
0
34
0
0
% R
% Ser:
0
17
17
0
25
9
0
34
0
50
9
0
17
42
0
% S
% Thr:
9
0
0
0
0
42
0
9
0
0
0
9
0
25
0
% T
% Val:
25
0
0
9
0
0
9
0
50
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
17
0
0
0
9
9
0
0
9
0
% W
% Tyr:
9
0
0
0
0
0
0
0
9
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _