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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW2
All Species:
15.76
Human Site:
T219
Identified Species:
31.52
UniProt:
Q9UKT8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKT8
NP_036296.2
454
51512
T219
E
W
S
S
G
A
R
T
Q
H
F
R
G
H
T
Chimpanzee
Pan troglodytes
XP_001157864
486
55209
T251
E
W
S
S
G
A
R
T
Q
H
F
R
G
H
T
Rhesus Macaque
Macaca mulatta
XP_001096076
455
51692
T219
E
W
S
S
G
A
R
T
Q
H
F
R
G
H
T
Dog
Lupus familis
XP_867821
389
44448
D168
L
C
T
V
F
S
V
D
Y
N
D
E
L
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q60584
422
47892
T201
F
D
E
Q
K
L
V
T
G
S
F
D
N
T
V
Rat
Rattus norvegicus
B2RZ17
454
51389
T219
E
W
S
S
G
A
R
T
Q
H
F
R
G
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PTR5
410
46646
H189
F
E
C
I
R
T
M
H
G
H
D
H
N
V
S
Frog
Xenopus laevis
Q91854
518
59489
K265
D
K
N
T
L
E
C
K
R
V
L
M
G
H
T
Zebra Danio
Brachydanio rerio
Q7T394
410
46494
H189
F
E
C
I
R
T
M
H
G
H
D
H
N
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203222
435
49086
F214
I
K
V
I
T
A
S
F
D
N
T
I
A
C
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39014
640
72817
T413
V
W
H
V
E
S
R
T
C
Y
T
L
R
G
H
Red Bread Mold
Neurospora crassa
Q01277
650
72171
E365
V
W
N
W
H
T
G
E
C
L
S
T
F
A
A
Conservation
Percent
Protein Identity:
100
93.4
95.5
85.6
N.A.
90.7
98.6
N.A.
N.A.
22
20.2
21.5
N.A.
N.A.
N.A.
N.A.
47.8
Protein Similarity:
100
93.4
97.3
85.6
N.A.
91.8
99.5
N.A.
N.A.
39.2
36.8
38.5
N.A.
N.A.
N.A.
N.A.
66.7
P-Site Identity:
100
100
100
0
N.A.
13.3
100
N.A.
N.A.
6.6
20
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
13.3
100
N.A.
N.A.
13.3
46.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.9
20.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
42
0
0
0
0
0
0
9
9
9
% A
% Cys:
0
9
17
0
0
0
9
0
17
0
0
0
0
9
0
% C
% Asp:
9
9
0
0
0
0
0
9
9
0
25
9
0
9
0
% D
% Glu:
34
17
9
0
9
9
0
9
0
0
0
9
0
0
0
% E
% Phe:
25
0
0
0
9
0
0
9
0
0
42
0
9
0
0
% F
% Gly:
0
0
0
0
34
0
9
0
25
0
0
0
42
9
0
% G
% His:
0
0
9
0
9
0
0
17
0
50
0
17
0
42
9
% H
% Ile:
9
0
0
25
0
0
0
0
0
0
0
9
0
0
9
% I
% Lys:
0
17
0
0
9
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
9
9
0
0
0
9
9
9
9
0
0
% L
% Met:
0
0
0
0
0
0
17
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
17
0
0
25
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
34
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
17
0
42
0
9
0
0
34
9
0
0
% R
% Ser:
0
0
34
34
0
17
9
0
0
9
9
0
0
0
17
% S
% Thr:
0
0
9
9
9
25
0
50
0
0
17
9
0
9
42
% T
% Val:
17
0
9
17
0
0
17
0
0
9
0
0
0
17
9
% V
% Trp:
0
50
0
9
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _