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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACSL6 All Species: 25.15
Human Site: S135 Identified Species: 46.11
UniProt: Q9UKU0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKU0 NP_001009185.1 697 77752 S135 D R A E F L G S G L L Q H N C
Chimpanzee Pan troglodytes XP_517555 698 77925 S135 E L S E C I G S A L I Q K G F
Rhesus Macaque Macaca mulatta XP_001084069 698 77742 S135 E M S E C L G S A L I Q K G F
Dog Lupus familis XP_849968 690 77241 S135 D R A E F L G S G L L Q H N C
Cat Felis silvestris
Mouse Mus musculus Q91WC3 697 77999 S135 K R A E F L G S G L L Q H D C
Rat Rattus norvegicus P33124 697 78162 S135 K R A E F L G S G L L Q H D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510992 806 89603 S244 K R A E F L G S G L L H H G C
Chicken Gallus gallus Q5ZKR7 763 84188 S146 K C W K A A K S F L K L V L E
Frog Xenopus laevis Q7ZYC4 739 81601 G153 Q C R I A A K G F I K L G L E
Zebra Danio Brachydanio rerio XP_001920939 633 70898 A128 I R F I I N T A E I S T V I C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3S9 666 73592 A129 I H A R G I I A G I Y T T N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S777 561 61292 P65 L S S V S D K P C L I V G S T
Baker's Yeast Sacchar. cerevisiae P39518 744 83419 S145 K R C H N I G S G I L S L V N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.7 64.6 92.9 N.A. 91.8 90.6 N.A. 75 23.9 24.2 68.1 N.A. 26.9 N.A. N.A. N.A.
Protein Similarity: 100 81.8 80 96.5 N.A. 95.5 94.5 N.A. 81.2 42.3 43.8 78.3 N.A. 47.6 N.A. N.A. N.A.
P-Site Identity: 100 33.3 40 100 N.A. 86.6 86.6 N.A. 80 13.3 0 13.3 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 60 60 100 N.A. 93.3 93.3 N.A. 80 20 6.6 26.6 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.6 30.6 N.A.
Protein Similarity: N.A. N.A. N.A. 39.6 47.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 47 0 16 16 0 16 16 0 0 0 0 0 0 % A
% Cys: 0 16 8 0 16 0 0 0 8 0 0 0 0 0 47 % C
% Asp: 16 0 0 0 0 8 0 0 0 0 0 0 0 16 0 % D
% Glu: 16 0 0 54 0 0 0 0 8 0 0 0 0 0 16 % E
% Phe: 0 0 8 0 39 0 0 0 16 0 0 0 0 0 16 % F
% Gly: 0 0 0 0 8 0 62 8 54 0 0 0 16 24 0 % G
% His: 0 8 0 8 0 0 0 0 0 0 0 8 39 0 0 % H
% Ile: 16 0 0 16 8 24 8 0 0 31 24 0 0 8 0 % I
% Lys: 39 0 0 8 0 0 24 0 0 0 16 0 16 0 0 % K
% Leu: 8 8 0 0 0 47 0 0 0 70 47 16 8 16 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 0 0 0 0 0 0 0 24 8 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 47 0 0 0 % Q
% Arg: 0 54 8 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 24 0 8 0 0 70 0 0 8 8 0 8 8 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 16 8 0 8 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 8 16 8 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _