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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGPTL2
All Species:
23.64
Human Site:
S475
Identified Species:
57.78
UniProt:
Q9UKU9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKU9
NP_036230.1
493
57104
S475
W
A
E
F
R
G
G
S
Y
S
L
K
K
V
V
Chimpanzee
Pan troglodytes
XP_520266
493
57027
S475
W
A
E
F
R
G
G
S
Y
S
L
K
K
V
V
Rhesus Macaque
Macaca mulatta
XP_001096546
493
57042
S475
W
A
E
F
R
G
G
S
Y
S
L
K
K
V
V
Dog
Lupus familis
XP_537840
493
57132
S475
W
A
E
F
R
G
G
S
Y
S
L
K
K
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9R045
493
57100
S475
W
A
E
F
R
G
G
S
Y
S
L
K
K
V
V
Rat
Rattus norvegicus
O35460
497
57442
G468
Y
T
A
G
Q
N
H
G
K
L
N
G
I
K
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515613
484
56082
S466
W
A
E
F
R
G
G
S
Y
S
L
K
K
V
V
Chicken
Gallus gallus
P14448
741
82420
Y706
G
G
H
Y
D
P
R
Y
N
V
P
Y
E
I
E
Frog
Xenopus laevis
Q5XK91
457
51018
Q440
W
S
S
W
T
G
W
Q
Y
S
L
K
F
T
E
Zebra Danio
Brachydanio rerio
NP_001119950
519
59512
A501
W
A
E
F
R
G
G
A
Y
S
L
K
K
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.5
96.7
N.A.
94.9
28.1
N.A.
88.6
24.1
27.3
77
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.8
97.7
N.A.
96.7
48.2
N.A.
94.5
40.2
44.2
84.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
0
40
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
20
53.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
10
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
70
0
0
0
0
0
0
0
0
0
10
0
20
% E
% Phe:
0
0
0
70
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
10
0
10
0
80
70
10
0
0
0
10
0
0
0
% G
% His:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
80
70
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
80
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
70
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
0
0
0
60
0
80
0
0
0
0
0
% S
% Thr:
0
10
0
0
10
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
70
70
% V
% Trp:
80
0
0
10
0
0
10
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
0
10
0
0
0
10
80
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _