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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HDAC9 All Species: 22.42
Human Site: S264 Identified Species: 49.33
UniProt: Q9UKV0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV0 NP_055522.1 1011 111297 S264 R M F E V T E S S V S S S S P
Chimpanzee Pan troglodytes XP_001150710 1008 110905 S261 R M F E V T E S S V S S S S P
Rhesus Macaque Macaca mulatta XP_001104208 1011 111383 S261 R M F E V T E S S V S S S S P
Dog Lupus familis XP_539456 875 97042 S181 Y T A A H H T S L D Q S S P P
Cat Felis silvestris
Mouse Mus musculus Q6NZM9 1076 118544 S289 R P L D V T D S A C S S A P G
Rat Rattus norvegicus Q99P99 1077 118634 S289 R P L D V T D S A C S S A P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510939 1082 119892 S293 R P L D V T D S A C N S A P G
Chicken Gallus gallus P83038 1080 119449 S289 R P L D V T D S A C N S A P G
Frog Xenopus laevis Q9YGY4 596 67288
Zebra Danio Brachydanio rerio Q6PBI4 582 65098
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17323 816 88964 A125 D R L K N M I A N R S K G E S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.5 84.5 N.A. 54.8 54.8 N.A. 54.6 55 41.8 38.1 N.A. N.A. N.A. 31.2 N.A.
Protein Similarity: 100 99.5 99.5 85.2 N.A. 68.7 68.7 N.A. 68.8 68.9 48.4 45.2 N.A. N.A. N.A. 48.8 N.A.
P-Site Identity: 100 100 100 26.6 N.A. 40 40 N.A. 33.3 33.3 0 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 66.6 66.6 N.A. 66.6 66.6 0 0 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 10 37 0 0 0 37 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 37 0 0 0 0 0 % C
% Asp: 10 0 0 37 0 0 37 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 28 0 0 28 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 37 % G
% His: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 46 0 0 0 0 0 10 0 0 0 0 0 0 % L
% Met: 0 28 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 10 0 19 0 0 0 0 % N
% Pro: 0 37 0 0 0 0 0 0 0 0 0 0 0 46 37 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 64 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 73 28 0 55 73 37 28 10 % S
% Thr: 0 10 0 0 0 64 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 64 0 0 0 0 28 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _