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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC9
All Species:
9.09
Human Site:
S376
Identified Species:
20
UniProt:
Q9UKV0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKV0
NP_055522.1
1011
111297
S376
G
G
S
I
P
A
S
S
S
H
P
H
V
T
L
Chimpanzee
Pan troglodytes
XP_001150710
1008
110905
S373
G
G
S
I
P
A
S
S
S
H
P
H
V
T
L
Rhesus Macaque
Macaca mulatta
XP_001104208
1011
111383
S373
G
G
S
I
P
A
S
S
S
H
P
H
V
T
L
Dog
Lupus familis
XP_539456
875
97042
P293
N
E
T
S
V
L
P
P
T
P
H
A
E
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZM9
1076
118544
E401
Y
L
S
T
S
P
L
E
R
D
G
A
A
A
H
Rat
Rattus norvegicus
Q99P99
1077
118634
L401
P
Y
L
S
T
S
P
L
E
R
D
G
G
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510939
1082
119892
L405
P
Y
L
S
T
T
T
L
E
R
D
G
G
T
A
Chicken
Gallus gallus
P83038
1080
119449
L401
P
Y
L
S
T
T
T
L
E
R
D
G
G
T
A
Frog
Xenopus laevis
Q9YGY4
596
67288
V17
S
Y
F
S
S
D
G
V
A
G
R
E
Q
L
L
Zebra Danio
Brachydanio rerio
Q6PBI4
582
65098
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17323
816
88964
R237
F
T
H
P
Q
L
K
R
S
D
S
E
T
S
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.5
84.5
N.A.
54.8
54.8
N.A.
54.6
55
41.8
38.1
N.A.
N.A.
N.A.
31.2
N.A.
Protein Similarity:
100
99.5
99.5
85.2
N.A.
68.7
68.7
N.A.
68.8
68.9
48.4
45.2
N.A.
N.A.
N.A.
48.8
N.A.
P-Site Identity:
100
100
100
0
N.A.
6.6
0
N.A.
6.6
6.6
6.6
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
6.6
6.6
N.A.
13.3
13.3
13.3
0
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
28
0
0
10
0
0
19
10
19
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
19
28
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
10
28
0
0
19
10
0
0
% E
% Phe:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
28
28
0
0
0
0
10
0
0
10
10
28
28
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
28
10
28
0
0
10
% H
% Ile:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
28
0
0
19
10
28
0
0
0
0
0
10
37
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
28
0
0
10
28
10
19
10
0
10
28
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
10
% Q
% Arg:
0
0
0
0
0
0
0
10
10
28
10
0
0
0
0
% R
% Ser:
10
0
37
46
19
10
28
28
37
0
10
0
0
10
0
% S
% Thr:
0
10
10
10
28
19
19
0
10
0
0
0
10
46
0
% T
% Val:
0
0
0
0
10
0
0
10
0
0
0
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _