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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 13.64
Human Site: S455 Identified Species: 21.43
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S455 G I T Q A S N S Q L N A M A H
Chimpanzee Pan troglodytes XP_001135064 580 66233 S392 G I T Q A S N S Q L N A M A H
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 L384 F P Q V P Y H L V L Q D L Q L
Dog Lupus familis XP_544395 453 51620 L285 Q V P Y H L V L Q D L Q L T R
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 S455 G I T Q A S N S Q L N A M A H
Rat Rattus norvegicus Q6Y290 419 46430 K251 K L T T R T V K K G D K E T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 S575 G I T Q A S N S Q L N A M A H
Frog Xenopus laevis Q5XHH7 595 65901 A409 G S S S G S S A R A G E T S N
Zebra Danio Brachydanio rerio Q803I8 625 68739 A432 S T A E A A S A A P G A M P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 I436 P M I S P F M I P P H F G Y L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 L395 E V G N S T R L R F N G G S F
Sea Urchin Strong. purpuratus XP_792411 845 93984 Q573 P Q A A H T S Q L D N M A R Q
Poplar Tree Populus trichocarpa XP_002303501 581 64513 E400 T G E V L A D E Q L A H Q I N
Maize Zea mays NP_001137060 503 56440 P335 T C R A P I V P A D N G R A A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 C292 L S S N D A T C I I C R E E M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 6.6 6.6 N.A. 100 6.6 N.A. N.A. 100 13.3 20 N.A. 0 N.A. 6.6 6.6
P-Site Similarity: 100 100 20 20 N.A. 100 33.3 N.A. N.A. 100 53.3 46.6 N.A. 13.3 N.A. 40 20
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 0 N.A. N.A.
P-Site Similarity: 33.3 13.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 14 34 20 0 14 14 7 7 34 7 34 7 % A
% Cys: 0 7 0 0 0 0 0 7 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 7 0 0 20 7 7 0 0 7 % D
% Glu: 7 0 7 7 0 0 0 7 0 0 0 7 14 7 0 % E
% Phe: 7 0 0 0 0 7 0 0 0 7 0 7 0 0 7 % F
% Gly: 34 7 7 0 7 0 0 0 0 7 14 14 14 0 7 % G
% His: 0 0 0 0 14 0 7 0 0 0 7 7 0 0 27 % H
% Ile: 0 27 7 0 0 7 0 7 7 7 0 0 0 7 0 % I
% Lys: 7 0 0 0 0 0 0 7 7 0 0 7 0 0 0 % K
% Leu: 7 7 0 0 7 7 0 20 7 40 7 0 14 0 14 % L
% Met: 0 7 0 0 0 0 7 0 0 0 0 7 34 0 7 % M
% Asn: 0 0 0 14 0 0 27 0 0 0 47 0 0 0 14 % N
% Pro: 14 7 7 0 20 0 0 7 7 14 0 0 0 7 0 % P
% Gln: 7 7 7 27 0 0 0 7 40 0 7 7 7 7 7 % Q
% Arg: 0 0 7 0 7 0 7 0 14 0 0 7 7 7 7 % R
% Ser: 7 14 14 14 7 34 20 27 0 0 0 0 0 14 0 % S
% Thr: 14 7 34 7 0 20 7 0 0 0 0 0 7 14 0 % T
% Val: 0 14 0 14 0 0 20 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 7 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _