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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 11.52
Human Site: S531 Identified Species: 18.1
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S531 D Q E E G E T S A Q T E R V P
Chimpanzee Pan troglodytes XP_001135064 580 66233 S468 D Q E E G E T S A Q T E R V P
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 T457 L S P R L E E T L D F G E V E
Dog Lupus familis XP_544395 453 51620 D358 P R L E E A L D F S E V E V E
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 S531 D L E E G E A S V Q T E R V P
Rat Rattus norvegicus Q6Y290 419 46430 V324 N L P C T D N V A F D M E R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 V651 D Q E D T G T V T Q T K R V P
Frog Xenopus laevis Q5XHH7 595 65901 A493 I H T L L D A A M L Q I N Q Y
Zebra Danio Brachydanio rerio Q803I8 625 68739 T519 N I H H Y L S T V A T L S P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 T511 R L Q L T A V T P A T A V N G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 N468 S A Q S T I E N I L E G R I G
Sea Urchin Strong. purpuratus XP_792411 845 93984 A648 Q A F Q P N Q A E D G D E D G
Poplar Tree Populus trichocarpa XP_002303501 581 64513 Q474 S V G L G G V Q M M M R H L A
Maize Zea mays NP_001137060 503 56440 P408 S R S G S P Q P T S S A P Q S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 G365 T G T S S S D G Q G S S V S A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 13.3 13.3 N.A. 80 6.6 N.A. N.A. 60 0 13.3 N.A. 6.6 N.A. 6.6 0
P-Site Similarity: 100 100 20 20 N.A. 80 20 N.A. N.A. 73.3 13.3 33.3 N.A. 20 N.A. 26.6 20
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 6.6 0 N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 13.3 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 0 0 14 14 14 20 14 0 14 0 0 14 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 27 0 0 7 0 14 7 7 0 14 7 7 0 7 0 % D
% Glu: 0 0 27 27 7 27 14 0 7 0 14 20 27 0 14 % E
% Phe: 0 0 7 0 0 0 0 0 7 7 7 0 0 0 0 % F
% Gly: 0 7 7 7 27 14 0 7 0 7 7 14 0 0 20 % G
% His: 0 7 7 7 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 7 7 0 0 0 7 0 0 7 0 0 7 0 7 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % K
% Leu: 7 20 7 20 14 7 7 0 7 14 0 7 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 14 7 7 7 0 0 0 % M
% Asn: 14 0 0 0 0 7 7 7 0 0 0 0 7 7 0 % N
% Pro: 7 0 14 0 7 7 0 7 7 0 0 0 7 7 34 % P
% Gln: 7 20 14 7 0 0 14 7 7 27 7 0 0 14 0 % Q
% Arg: 7 14 0 7 0 0 0 0 0 0 0 7 34 7 0 % R
% Ser: 20 7 7 14 14 7 7 20 0 14 14 7 7 7 7 % S
% Thr: 7 0 14 0 27 0 20 20 14 0 40 0 0 0 0 % T
% Val: 0 7 0 0 0 0 14 14 14 0 0 7 14 40 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _