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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 15.76
Human Site: S542 Identified Species: 24.76
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S542 E R V P L D L S P R L E E T L
Chimpanzee Pan troglodytes XP_001135064 580 66233 S479 E R V P L D L S P R L E E T L
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 S468 G E V E V E P S E V E D F E A
Dog Lupus familis XP_544395 453 51620 G369 V E V E P S E G E D F E A R G
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 S542 E R V P L D L S P R L E E T L
Rat Rattus norvegicus Q6Y290 419 46430 Q335 M E R L T R T Q A V N R R S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 N662 K R V P L E L N S R L E E M G
Frog Xenopus laevis Q5XHH7 595 65901 L504 I N Q Y L T V L A S I G P P Q
Zebra Danio Brachydanio rerio Q803I8 625 68739 T530 L S P P R S E T N T G E T S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 S522 A V N G S A D S S V Y D M P S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 S479 G R I G M N A S F M P G G V L
Sea Urchin Strong. purpuratus XP_792411 845 93984 Y659 D E D G G L L Y R Q A R H H R
Poplar Tree Populus trichocarpa XP_002303501 581 64513 E485 R H L A S V G E T Y A Q T A L
Maize Zea mays NP_001137060 503 56440 S419 A P Q S E A S S S N H Q S Q K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 E376 S V S A A A S E N M S R H E A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 13.3 13.3 N.A. 100 0 N.A. N.A. 60 6.6 13.3 N.A. 6.6 N.A. 20 6.6
P-Site Similarity: 100 100 33.3 13.3 N.A. 100 6.6 N.A. N.A. 80 20 26.6 N.A. 13.3 N.A. 40 20
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: 20 13.3 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 14 7 20 7 0 14 0 14 0 7 7 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 20 7 0 0 7 0 14 0 0 0 % D
% Glu: 20 27 0 14 7 14 14 14 14 0 7 40 27 14 7 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 7 0 7 0 0 % F
% Gly: 14 0 0 20 7 0 7 7 0 0 7 14 7 0 14 % G
% His: 0 7 0 0 0 0 0 0 0 0 7 0 14 7 0 % H
% Ile: 7 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 7 0 7 7 34 7 34 7 0 0 27 0 0 0 34 % L
% Met: 7 0 0 0 7 0 0 0 0 14 0 0 7 7 0 % M
% Asn: 0 7 7 0 0 7 0 7 14 7 7 0 0 0 0 % N
% Pro: 0 7 7 34 7 0 7 0 20 0 7 0 7 14 0 % P
% Gln: 0 0 14 0 0 0 0 7 0 7 0 14 0 7 7 % Q
% Arg: 7 34 7 0 7 7 0 0 7 27 0 20 7 7 7 % R
% Ser: 7 7 7 7 14 14 14 47 20 7 7 0 7 14 7 % S
% Thr: 0 0 0 0 7 7 7 7 7 7 0 0 14 20 0 % T
% Val: 7 14 40 0 7 7 7 0 0 20 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 7 0 7 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _