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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 11.52
Human Site: S559 Identified Species: 18.1
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S559 G E V E V E P S E V E D F E A
Chimpanzee Pan troglodytes XP_001135064 580 66233 S496 G E V E V E P S E V E D F E A
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 D485 S R F S K S A D E R Q R M L V
Dog Lupus familis XP_544395 453 51620 R386 F S K S A D E R Q R M L V Q R
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 I559 S E V E L E P I E V E D F E A
Rat Rattus norvegicus Q6Y290 419 46430 L352 D L A N D S S L G L E P L R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 S679 S E V E A E P S E A E D F E A
Frog Xenopus laevis Q5XHH7 595 65901 S521 V S S S S S S S A S A S T E P
Zebra Danio Brachydanio rerio Q803I8 625 68739 T547 N V E S S P S T A N T E T A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 E539 A T A M A Q L E T H Q V T P T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 N496 E L S D E S E N E I E Y E E P
Sea Urchin Strong. purpuratus XP_792411 845 93984 T676 E E G P S D I T T R G M E G S
Poplar Tree Populus trichocarpa XP_002303501 581 64513 M502 A A W S L W P M S P S Q A T P
Maize Zea mays NP_001137060 503 56440 S436 E T Q L Q N S S D G L V P L P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 S393 Q A A A S A A S I Y G R S I V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 6.6 0 N.A. 80 6.6 N.A. N.A. 80 13.3 0 N.A. 0 N.A. 20 6.6
P-Site Similarity: 100 100 13.3 20 N.A. 86.6 13.3 N.A. N.A. 80 13.3 13.3 N.A. 13.3 N.A. 40 26.6
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 13.3 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 14 20 7 20 7 14 0 14 7 7 0 7 7 27 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 7 7 14 0 7 7 0 0 27 0 0 0 % D
% Glu: 20 34 7 27 7 27 14 7 40 0 40 7 14 40 0 % E
% Phe: 7 0 7 0 0 0 0 0 0 0 0 0 27 0 0 % F
% Gly: 14 0 7 0 0 0 0 0 7 7 14 0 0 7 7 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 7 7 7 0 0 0 7 0 % I
% Lys: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 14 0 7 14 0 7 7 0 7 7 7 7 14 0 % L
% Met: 0 0 0 7 0 0 0 7 0 0 7 7 7 0 0 % M
% Asn: 7 0 0 7 0 7 0 7 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 7 0 7 34 0 0 7 0 7 7 7 27 % P
% Gln: 7 0 7 0 7 7 0 0 7 0 14 7 0 7 0 % Q
% Arg: 0 7 0 0 0 0 0 7 0 20 0 14 0 7 7 % R
% Ser: 20 14 14 34 27 27 27 40 7 7 7 7 7 0 7 % S
% Thr: 0 14 0 0 0 0 0 14 14 0 7 0 20 7 14 % T
% Val: 7 7 27 0 14 0 0 0 0 20 0 14 7 0 14 % V
% Trp: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _