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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 16.67
Human Site: S569 Identified Species: 26.19
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S569 E D F E A R G S R F S K S A D
Chimpanzee Pan troglodytes XP_001135064 580 66233 S506 E D F E A R G S R F S K S A D
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 K495 Q R M L V Q R K D E L L Q Q A
Dog Lupus familis XP_544395 453 51620 D396 M L V Q R K D D L L Q Q A R K
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 S569 E D F E A R G S R F S K S A D
Rat Rattus norvegicus Q6Y290 419 46430 I362 E P L R T S G I S P L P Q D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 S689 E D F E A R G S R F S K S A D
Frog Xenopus laevis Q5XHH7 595 65901 S531 A S T E P T T S S V S E P V I
Zebra Danio Brachydanio rerio Q803I8 625 68739 I557 T E T A G Q E I Q S Q S G E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 A549 Q V T P T A A A S S A S P T M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 I506 E Y E E P A E I V Q E P D N G
Sea Urchin Strong. purpuratus XP_792411 845 93984 N686 G M E G S E D N A A N W T R P
Poplar Tree Populus trichocarpa XP_002303501 581 64513 S512 S Q A T P S G S S T P P A A A
Maize Zea mays NP_001137060 503 56440 A446 L V P L P F S A D G V V G S G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 S403 G R S I V Y P S S A N T L V W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 0 0 N.A. 100 13.3 N.A. N.A. 100 20 0 N.A. 0 N.A. 13.3 0
P-Site Similarity: 100 100 13.3 26.6 N.A. 100 13.3 N.A. N.A. 100 26.6 20 N.A. 20 N.A. 13.3 26.6
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 20 0 N.A. 6.6 N.A. N.A.
P-Site Similarity: 26.6 13.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 27 14 7 14 7 14 7 0 14 34 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 27 0 0 0 0 14 7 14 0 0 0 7 7 27 % D
% Glu: 40 7 14 40 0 7 14 0 0 7 7 7 0 7 0 % E
% Phe: 0 0 27 0 0 7 0 0 0 27 0 0 0 0 0 % F
% Gly: 14 0 0 7 7 0 40 0 0 7 0 0 14 0 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 20 0 0 0 0 0 0 7 % I
% Lys: 0 0 0 0 0 7 0 7 0 0 0 27 0 0 7 % K
% Leu: 7 7 7 14 0 0 0 0 7 7 14 7 7 0 0 % L
% Met: 7 7 7 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 14 0 0 7 0 % N
% Pro: 0 7 7 7 27 0 7 0 0 7 7 20 14 0 7 % P
% Gln: 14 7 0 7 0 14 0 0 7 7 14 7 14 7 0 % Q
% Arg: 0 14 0 7 7 27 7 0 27 0 0 0 0 14 0 % R
% Ser: 7 7 7 0 7 14 7 47 34 14 34 14 27 7 7 % S
% Thr: 7 0 20 7 14 7 7 0 0 7 0 7 7 7 0 % T
% Val: 0 14 7 0 14 0 0 0 7 7 7 7 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % W
% Tyr: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _