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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 14.85
Human Site: S574 Identified Species: 23.33
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S574 R G S R F S K S A D E R Q R M
Chimpanzee Pan troglodytes XP_001135064 580 66233 S511 R G S R F S K S A D E R Q R M
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 Q500 Q R K D E L L Q Q A R K R F L
Dog Lupus familis XP_544395 453 51620 A401 K D D L L Q Q A R K R F L N R
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 S574 R G S R F S K S A D E R Q R M
Rat Rattus norvegicus Q6Y290 419 46430 Q367 S G I S P L P Q D G E L T P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 S694 R G S R F S K S A D E R Q R M
Frog Xenopus laevis Q5XHH7 595 65901 P536 T T S S V S E P V I D T S S I
Zebra Danio Brachydanio rerio Q803I8 625 68739 G562 Q E I Q S Q S G E S I N G A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 P554 A A A S S A S P T M P A E K V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 D511 A E I V Q E P D N G R Q R T W
Sea Urchin Strong. purpuratus XP_792411 845 93984 T691 E D N A A N W T R P E S G A S
Poplar Tree Populus trichocarpa XP_002303501 581 64513 A517 S G S S T P P A A A G R H P G
Maize Zea mays NP_001137060 503 56440 G451 F S A D G V V G S G T S T R D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 L408 Y P S S A N T L V W S Q G N S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 0 0 N.A. 100 13.3 N.A. N.A. 100 13.3 0 N.A. 0 N.A. 0 6.6
P-Site Similarity: 100 100 26.6 20 N.A. 100 13.3 N.A. N.A. 100 33.3 13.3 N.A. 33.3 N.A. 13.3 26.6
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 26.6 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 33.3 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 14 7 14 7 0 14 34 14 0 7 0 14 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 7 14 0 0 0 7 7 27 7 0 0 0 7 % D
% Glu: 7 14 0 0 7 7 7 0 7 0 40 0 7 0 0 % E
% Phe: 7 0 0 0 27 0 0 0 0 0 0 7 0 7 0 % F
% Gly: 0 40 0 0 7 0 0 14 0 20 7 0 20 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 20 0 0 0 0 0 0 7 7 0 0 0 7 % I
% Lys: 7 0 7 0 0 0 27 0 0 7 0 7 0 7 0 % K
% Leu: 0 0 0 7 7 14 7 7 0 0 0 7 7 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 27 % M
% Asn: 0 0 7 0 0 14 0 0 7 0 0 7 0 14 0 % N
% Pro: 0 7 0 0 7 7 20 14 0 7 7 0 0 14 0 % P
% Gln: 14 0 0 7 7 14 7 14 7 0 0 14 27 0 0 % Q
% Arg: 27 7 0 27 0 0 0 0 14 0 20 34 14 34 14 % R
% Ser: 14 7 47 34 14 34 14 27 7 7 7 14 7 7 14 % S
% Thr: 7 7 0 0 7 0 7 7 7 0 7 7 14 7 0 % T
% Val: 0 0 0 7 7 7 7 0 14 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 7 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _