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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 18.48
Human Site: S601 Identified Species: 29.05
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S601 R K R F L N K S S E D D A A S
Chimpanzee Pan troglodytes XP_001135064 580 66233 S538 R K R F L N K S S E D D A A S
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 A515 N K S S E D D A A S E S F L P
Dog Lupus familis XP_544395 453 51620 S416 S S E V E S A S T S E S C L T
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 S601 R K R F L N K S S E D D G A S
Rat Rattus norvegicus Q6Y290 419 46430 V382 T G E I N I A V T K E W F I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 T721 R K R Y L N K T S D E E L S T
Frog Xenopus laevis Q5XHH7 595 65901 A553 T D S S Q Q S A S P V P V N V
Zebra Danio Brachydanio rerio Q803I8 625 68739 T577 G F S Q P D S T T E G E K D V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 A579 E D D I P S T A T E A V S I P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 G526 T K L S S S S G D E D L S Y Y
Sea Urchin Strong. purpuratus XP_792411 845 93984 S767 T Q Q G T S R S Q P S M S S T
Poplar Tree Populus trichocarpa XP_002303501 581 64513 H533 L H M R T A S H S T N D F I A
Maize Zea mays NP_001137060 503 56440 A466 L E N S L Q K A Q E N F I K S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 E423 L L P Q T E V E A Q R R F L E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 6.6 6.6 N.A. 93.3 0 N.A. N.A. 46.6 6.6 6.6 N.A. 6.6 N.A. 20 6.6
P-Site Similarity: 100 100 33.3 33.3 N.A. 93.3 20 N.A. N.A. 93.3 13.3 33.3 N.A. 33.3 N.A. 33.3 53.3
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 13.3 26.6 N.A. 0 N.A. N.A.
P-Site Similarity: 26.6 46.6 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 14 27 14 0 7 0 14 20 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 14 7 0 0 14 7 0 7 7 27 27 0 7 0 % D
% Glu: 7 7 14 0 14 7 0 7 0 47 27 14 0 0 7 % E
% Phe: 0 7 0 20 0 0 0 0 0 0 0 7 27 0 0 % F
% Gly: 7 7 0 7 0 0 0 7 0 0 7 0 7 0 0 % G
% His: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 14 0 7 0 0 0 0 0 0 7 20 7 % I
% Lys: 0 40 0 0 0 0 34 0 0 7 0 0 7 7 0 % K
% Leu: 20 7 7 0 34 0 0 0 0 0 0 7 7 20 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 7 0 7 0 7 27 0 0 0 0 14 0 0 7 0 % N
% Pro: 0 0 7 0 14 0 0 0 0 14 0 7 0 0 14 % P
% Gln: 0 7 7 14 7 14 0 0 14 7 0 0 0 0 0 % Q
% Arg: 27 0 27 7 0 0 7 0 0 0 7 7 0 0 0 % R
% Ser: 7 7 20 27 7 27 27 34 40 14 7 14 20 14 27 % S
% Thr: 27 0 0 0 20 0 7 14 27 7 0 0 0 0 20 % T
% Val: 0 0 0 7 0 0 7 7 0 0 7 7 7 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _