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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 17.58
Human Site: S608 Identified Species: 27.62
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S608 S S E D D A A S E S F L P S E
Chimpanzee Pan troglodytes XP_001135064 580 66233 S545 S S E D D A A S E S F L P S E
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 P522 A A S E S F L P S E G A S S D
Dog Lupus familis XP_544395 453 51620 T423 S T S E S C L T S E G T N S D
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 S608 S S E D D G A S E R L L P S E
Rat Rattus norvegicus Q6Y290 419 46430 I389 V T K E W F I I A S F G L L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 T728 T S D E E L S T E K P S V P E
Frog Xenopus laevis Q5XHH7 595 65901 V560 A S P V P V N V E T L G G A E
Zebra Danio Brachydanio rerio Q803I8 625 68739 V584 T T E G E K D V K E E D E D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 P586 A T E A V S I P N S D A D F E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 Y533 G D E D L S Y Y E I Q R A K M
Sea Urchin Strong. purpuratus XP_792411 845 93984 T774 S Q P S M S S T Y S A P P P S
Poplar Tree Populus trichocarpa XP_002303501 581 64513 A540 H S T N D F I A N I L A M A E
Maize Zea mays NP_001137060 503 56440 S473 A Q E N F I K S Q I E M L Q I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 E430 E A Q R R F L E S Q I E V L T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 6.6 13.3 N.A. 80 13.3 N.A. N.A. 20 20 6.6 N.A. 20 N.A. 20 20
P-Site Similarity: 100 100 33.3 40 N.A. 80 33.3 N.A. N.A. 60 40 40 N.A. 40 N.A. 26.6 40
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 20 13.3 N.A. 0 N.A. N.A.
P-Site Similarity: 40 40 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 27 14 0 7 0 14 20 7 7 0 7 20 7 14 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 27 27 0 7 0 0 0 7 7 7 7 20 % D
% Glu: 7 0 47 27 14 0 0 7 40 20 14 7 7 0 47 % E
% Phe: 0 0 0 0 7 27 0 0 0 0 20 0 0 7 0 % F
% Gly: 7 0 0 7 0 7 0 0 0 0 14 14 7 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 20 7 0 20 7 0 0 0 7 % I
% Lys: 0 0 7 0 0 7 7 0 7 7 0 0 0 7 0 % K
% Leu: 0 0 0 0 7 7 20 0 0 0 20 20 14 14 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 7 7 0 7 % M
% Asn: 0 0 0 14 0 0 7 0 14 0 0 0 7 0 0 % N
% Pro: 0 0 14 0 7 0 0 14 0 0 7 7 27 14 0 % P
% Gln: 0 14 7 0 0 0 0 0 7 7 7 0 0 7 0 % Q
% Arg: 0 0 0 7 7 0 0 0 0 7 0 7 0 0 0 % R
% Ser: 34 40 14 7 14 20 14 27 20 34 0 7 7 34 14 % S
% Thr: 14 27 7 0 0 0 0 20 0 7 0 7 0 0 7 % T
% Val: 7 0 0 7 7 7 0 14 0 0 0 0 14 0 0 % V
% Trp: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 7 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _