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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 10.3
Human Site: S610 Identified Species: 16.19
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S610 E D D A A S E S F L P S E G A
Chimpanzee Pan troglodytes XP_001135064 580 66233 S547 E D D A A S E S F L P S E G A
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 E524 S E S F L P S E G A S S D P V
Dog Lupus familis XP_544395 453 51620 E425 S E S C L T S E G T N S D P V
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 R610 E D D G A S E R L L P S E G T
Rat Rattus norvegicus Q6Y290 419 46430 S391 K E W F I I A S F G L L S A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 K730 D E E L S T E K P S V P E G A
Frog Xenopus laevis Q5XHH7 595 65901 T562 P V P V N V E T L G G A E G G
Zebra Danio Brachydanio rerio Q803I8 625 68739 E586 E G E K D V K E E D E D D G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 S588 E A V S I P N S D A D F E E N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 I535 E D L S Y Y E I Q R A K M I E
Sea Urchin Strong. purpuratus XP_792411 845 93984 S776 P S M S S T Y S A P P P S A A
Poplar Tree Populus trichocarpa XP_002303501 581 64513 I542 T N D F I A N I L A M A E T V
Maize Zea mays NP_001137060 503 56440 I475 E N F I K S Q I E M L Q I Q L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 Q432 Q R R F L E S Q I E V L T N Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 6.6 6.6 N.A. 73.3 13.3 N.A. N.A. 26.6 20 13.3 N.A. 20 N.A. 20 20
P-Site Similarity: 100 100 20 26.6 N.A. 73.3 26.6 N.A. N.A. 60 33.3 33.3 N.A. 26.6 N.A. 26.6 40
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 0 N.A. N.A.
P-Site Similarity: 33.3 33.3 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 14 20 7 7 0 7 20 7 14 0 14 27 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 27 27 0 7 0 0 0 7 7 7 7 20 0 0 % D
% Glu: 47 27 14 0 0 7 40 20 14 7 7 0 47 7 14 % E
% Phe: 0 0 7 27 0 0 0 0 20 0 0 7 0 0 0 % F
% Gly: 0 7 0 7 0 0 0 0 14 14 7 0 0 40 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 20 7 0 20 7 0 0 0 7 7 0 % I
% Lys: 7 0 0 7 7 0 7 7 0 0 0 7 0 0 0 % K
% Leu: 0 0 7 7 20 0 0 0 20 20 14 14 0 0 14 % L
% Met: 0 0 7 0 0 0 0 0 0 7 7 0 7 0 0 % M
% Asn: 0 14 0 0 7 0 14 0 0 0 7 0 0 7 7 % N
% Pro: 14 0 7 0 0 14 0 0 7 7 27 14 0 14 0 % P
% Gln: 7 0 0 0 0 0 7 7 7 0 0 7 0 7 7 % Q
% Arg: 0 7 7 0 0 0 0 7 0 7 0 0 0 0 0 % R
% Ser: 14 7 14 20 14 27 20 34 0 7 7 34 14 0 0 % S
% Thr: 7 0 0 0 0 20 0 7 0 7 0 0 7 7 7 % T
% Val: 0 7 7 7 0 14 0 0 0 0 14 0 0 0 20 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 7 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _