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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMFR All Species: 14.24
Human Site: S619 Identified Species: 22.38
UniProt: Q9UKV5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKV5 NP_001135.3 643 72996 S619 L P S E G A S S D P V T L R R
Chimpanzee Pan troglodytes XP_001135064 580 66233 S556 L P S E G A S S D P V T L R R
Rhesus Macaque Macaca mulatta XP_001091030 552 63193 L533 A S S D P V T L R R R M L A A
Dog Lupus familis XP_544395 453 51620 L434 T N S D P V T L R R R M L A A
Cat Felis silvestris
Mouse Mus musculus Q9R049 643 73087 S619 L P S E G T S S D P V T L R R
Rat Rattus norvegicus Q6Y290 419 46430 L400 G L L S A L T L C Y M I I R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414064 763 87868 A739 S V P E G A S A D P V T L R R
Frog Xenopus laevis Q5XHH7 595 65901 T571 G G A E G G E T P T E E P D N
Zebra Danio Brachydanio rerio Q803I8 625 68739 S595 D E D D G E P S A A E L R R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95SP2 626 69254 S597 A D F E E N S S E L G E L R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90859 564 64691 Y544 R A K M I E T Y R R K Y L E S
Sea Urchin Strong. purpuratus XP_792411 845 93984 Q785 P P P S A A S Q E T S A T R H
Poplar Tree Populus trichocarpa XP_002303501 581 64513 E551 A M A E T V R E V L P H V P D
Maize Zea mays NP_001137060 503 56440 M484 M L Q I Q L Q M V Q R G A A G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_849843 460 52108 R441 E V L T N Q L R L L E K P T T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.5 66.5 N.A. 94.4 20.2 N.A. N.A. 69.8 20.2 23.7 N.A. 23 N.A. 21.7 40.5
Protein Similarity: 100 85.2 84.7 67.8 N.A. 96.5 34.8 N.A. N.A. 76.1 36.7 39.9 N.A. 42.6 N.A. 42.4 52.7
P-Site Identity: 100 100 13.3 13.3 N.A. 93.3 6.6 N.A. N.A. 73.3 13.3 26.6 N.A. 33.3 N.A. 6.6 26.6
P-Site Similarity: 100 100 26.6 26.6 N.A. 93.3 26.6 N.A. N.A. 80 26.6 33.3 N.A. 46.6 N.A. 13.3 33.3
Percent
Protein Identity: 23.7 24.5 N.A. 25.3 N.A. N.A.
Protein Similarity: 41.5 40.2 N.A. 40.7 N.A. N.A.
P-Site Identity: 6.6 0 N.A. 0 N.A. N.A.
P-Site Similarity: 20 6.6 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 7 14 0 14 27 0 7 7 7 0 7 7 20 20 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 7 7 7 20 0 0 0 0 27 0 0 0 0 7 7 % D
% Glu: 7 7 0 47 7 14 7 7 14 0 20 14 0 7 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 7 0 0 40 7 0 0 0 0 7 7 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % H
% Ile: 0 0 0 7 7 0 0 0 0 0 0 7 7 0 0 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 7 7 0 0 7 % K
% Leu: 20 14 14 0 0 14 7 20 7 20 0 7 54 0 0 % L
% Met: 7 7 0 7 0 0 0 7 0 0 7 14 0 0 0 % M
% Asn: 0 7 0 0 7 7 0 0 0 0 0 0 0 0 7 % N
% Pro: 7 27 14 0 14 0 7 0 7 27 7 0 14 7 0 % P
% Gln: 0 0 7 0 7 7 7 7 0 7 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 7 7 20 20 20 0 7 54 34 % R
% Ser: 7 7 34 14 0 0 40 34 0 0 7 0 0 0 7 % S
% Thr: 7 0 0 7 7 7 27 7 0 14 0 27 7 7 7 % T
% Val: 0 14 0 0 0 20 0 0 14 0 27 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 7 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _