KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMFR
All Species:
14.55
Human Site:
T178
Identified Species:
22.86
UniProt:
Q9UKV5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKV5
NP_001135.3
643
72996
T178
Y
L
S
F
S
P
T
T
P
M
S
S
H
G
R
Chimpanzee
Pan troglodytes
XP_001135064
580
66233
H151
I
H
L
W
D
L
N
H
E
G
T
W
E
G
K
Rhesus Macaque
Macaca mulatta
XP_001091030
552
63193
L144
V
R
T
A
H
V
I
L
R
Y
V
I
H
L
W
Dog
Lupus familis
XP_544395
453
51620
Y45
T
A
H
V
I
L
R
Y
V
I
H
L
W
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R049
643
73087
T178
Y
L
S
F
S
P
T
T
P
M
S
S
H
G
R
Rat
Rattus norvegicus
Q6Y290
419
46430
R11
A
A
R
A
G
P
A
R
L
A
A
L
A
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414064
763
87868
T298
Y
L
S
F
S
P
T
T
P
M
S
S
H
I
R
Frog
Xenopus laevis
Q5XHH7
595
65901
T159
H
A
Y
N
S
L
V
T
R
G
A
S
V
Q
L
Zebra Danio
Brachydanio rerio
Q803I8
625
68739
Y178
Q
L
V
F
G
F
E
Y
A
I
L
M
T
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95SP2
626
69254
Q169
L
V
R
G
P
T
V
Q
L
V
F
G
F
E
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90859
564
64691
M152
G
H
R
V
M
P
W
M
I
W
G
G
I
C
A
Sea Urchin
Strong. purpuratus
XP_792411
845
93984
T288
Y
L
A
F
S
P
T
T
S
S
K
T
H
S
L
Poplar Tree
Populus trichocarpa
XP_002303501
581
64513
A151
R
L
N
A
S
P
S
A
T
P
W
T
Y
F
R
Maize
Zea mays
NP_001137060
503
56440
F95
I
L
F
A
V
T
I
F
R
Q
D
F
S
V
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_849843
460
52108
V52
V
L
L
N
M
G
L
V
L
M
L
S
L
W
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
84.5
66.5
N.A.
94.4
20.2
N.A.
N.A.
69.8
20.2
23.7
N.A.
23
N.A.
21.7
40.5
Protein Similarity:
100
85.2
84.7
67.8
N.A.
96.5
34.8
N.A.
N.A.
76.1
36.7
39.9
N.A.
42.6
N.A.
42.4
52.7
P-Site Identity:
100
6.6
6.6
0
N.A.
100
6.6
N.A.
N.A.
93.3
20
13.3
N.A.
0
N.A.
6.6
53.3
P-Site Similarity:
100
26.6
13.3
6.6
N.A.
100
13.3
N.A.
N.A.
93.3
33.3
20
N.A.
13.3
N.A.
6.6
66.6
Percent
Protein Identity:
23.7
24.5
N.A.
25.3
N.A.
N.A.
Protein Similarity:
41.5
40.2
N.A.
40.7
N.A.
N.A.
P-Site Identity:
26.6
6.6
N.A.
20
N.A.
N.A.
P-Site Similarity:
53.3
6.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
7
27
0
0
7
7
7
7
14
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
0
7
0
0
7
0
% D
% Glu:
0
0
0
0
0
0
7
0
7
0
0
0
7
7
0
% E
% Phe:
0
0
7
34
0
7
0
7
0
0
7
7
7
7
0
% F
% Gly:
7
0
0
7
14
7
0
0
0
14
7
14
0
20
0
% G
% His:
7
14
7
0
7
0
0
7
0
0
7
0
34
0
0
% H
% Ile:
14
0
0
0
7
0
14
0
7
14
0
7
7
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% K
% Leu:
7
54
14
0
0
20
7
7
20
0
14
14
7
14
27
% L
% Met:
0
0
0
0
14
0
0
7
0
27
0
7
0
7
0
% M
% Asn:
0
0
7
14
0
0
7
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
7
47
0
0
20
7
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
7
0
7
0
0
0
7
0
% Q
% Arg:
7
7
20
0
0
0
7
7
20
0
0
0
0
0
27
% R
% Ser:
0
0
20
0
40
0
7
0
7
7
20
34
7
7
7
% S
% Thr:
7
0
7
0
0
14
27
34
7
0
7
14
7
0
0
% T
% Val:
14
7
7
14
7
7
14
7
7
7
7
0
7
7
7
% V
% Trp:
0
0
0
7
0
0
7
0
0
7
7
7
7
7
7
% W
% Tyr:
27
0
7
0
0
0
0
14
0
7
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _