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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMFR
All Species:
16.06
Human Site:
Y258
Identified Species:
25.24
UniProt:
Q9UKV5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKV5
NP_001135.3
643
72996
Y258
E
G
K
G
T
Y
V
Y
Y
T
D
F
V
M
E
Chimpanzee
Pan troglodytes
XP_001135064
580
66233
F231
V
G
N
M
E
A
R
F
A
V
A
T
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001091030
552
63193
Y224
R
I
R
R
H
K
N
Y
L
R
V
V
G
N
M
Dog
Lupus familis
XP_544395
453
51620
R125
R
R
H
K
N
Y
L
R
V
V
G
N
M
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R049
643
73087
Y258
E
G
K
G
T
Y
V
Y
Y
T
D
F
V
M
E
Rat
Rattus norvegicus
Q6Y290
419
46430
P91
A
D
H
L
G
C
D
P
Q
T
R
F
F
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414064
763
87868
Y378
E
G
K
G
T
Y
V
Y
Y
T
D
F
V
M
E
Frog
Xenopus laevis
Q5XHH7
595
65901
I239
H
T
F
P
L
F
A
I
R
P
M
Y
L
A
M
Zebra Danio
Brachydanio rerio
Q803I8
625
68739
A258
A
M
R
Q
F
K
K
A
V
T
D
A
I
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95SP2
626
69254
T249
V
F
R
P
M
F
F
T
I
R
N
F
R
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90859
564
64691
Y232
L
A
V
F
R
S
T
Y
I
L
F
R
C
I
S
Sea Urchin
Strong. purpuratus
XP_792411
845
93984
Y368
E
N
R
G
S
L
I
Y
H
T
E
L
V
L
E
Poplar Tree
Populus trichocarpa
XP_002303501
581
64513
R231
G
N
S
A
N
C
Q
R
F
K
F
F
D
A
I
Maize
Zea mays
NP_001137060
503
56440
F175
E
A
S
V
A
I
F
F
S
F
E
Y
T
I
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_849843
460
52108
S132
E
Y
I
E
T
T
P
S
V
T
L
L
S
H
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
84.5
66.5
N.A.
94.4
20.2
N.A.
N.A.
69.8
20.2
23.7
N.A.
23
N.A.
21.7
40.5
Protein Similarity:
100
85.2
84.7
67.8
N.A.
96.5
34.8
N.A.
N.A.
76.1
36.7
39.9
N.A.
42.6
N.A.
42.4
52.7
P-Site Identity:
100
13.3
6.6
6.6
N.A.
100
13.3
N.A.
N.A.
100
0
20
N.A.
6.6
N.A.
6.6
40
P-Site Similarity:
100
20
13.3
20
N.A.
100
20
N.A.
N.A.
100
20
33.3
N.A.
26.6
N.A.
13.3
80
Percent
Protein Identity:
23.7
24.5
N.A.
25.3
N.A.
N.A.
Protein Similarity:
41.5
40.2
N.A.
40.7
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
20
N.A.
N.A.
P-Site Similarity:
13.3
33.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
0
7
7
7
7
7
7
0
7
7
0
14
14
% A
% Cys:
0
0
0
0
0
14
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
7
0
0
0
0
7
0
0
0
27
0
7
0
0
% D
% Glu:
40
0
0
7
7
0
0
0
0
0
14
0
0
14
34
% E
% Phe:
0
7
7
7
7
14
14
14
7
7
14
40
7
0
0
% F
% Gly:
7
27
0
27
7
0
0
0
0
0
7
0
7
0
0
% G
% His:
7
0
14
0
7
0
0
0
7
0
0
0
0
7
0
% H
% Ile:
0
7
7
0
0
7
7
7
14
0
0
0
7
14
7
% I
% Lys:
0
0
20
7
0
14
7
0
0
7
0
0
0
7
0
% K
% Leu:
7
0
0
7
7
7
7
0
7
7
7
14
7
7
7
% L
% Met:
0
7
0
7
7
0
0
0
0
0
7
0
7
27
14
% M
% Asn:
0
14
7
0
14
0
7
0
0
0
7
7
0
7
0
% N
% Pro:
0
0
0
14
0
0
7
7
0
7
0
0
7
0
7
% P
% Gln:
0
0
0
7
0
0
7
0
7
0
0
0
0
0
0
% Q
% Arg:
14
7
27
7
7
0
7
14
7
14
7
7
7
0
0
% R
% Ser:
0
0
14
0
7
7
0
7
7
0
0
0
7
0
14
% S
% Thr:
0
7
0
0
27
7
7
7
0
47
0
7
7
0
0
% T
% Val:
14
0
7
7
0
0
20
0
20
14
7
7
27
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
27
0
40
20
0
0
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _