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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2C2
All Species:
31.82
Human Site:
S469
Identified Species:
58.33
UniProt:
Q9UKV8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKV8
NP_001158095.1
859
97208
S469
C
T
E
V
H
L
K
S
F
T
E
Q
L
R
K
Chimpanzee
Pan troglodytes
XP_001142838
813
92351
G441
D
A
G
M
P
I
Q
G
Q
P
C
F
C
K
Y
Rhesus Macaque
Macaca mulatta
XP_001100725
1053
117937
S663
C
T
E
V
H
L
K
S
F
T
E
Q
L
R
K
Dog
Lupus familis
XP_532338
899
101246
S509
C
T
E
V
H
L
K
S
F
T
E
Q
L
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CJG0
860
97305
S470
C
T
E
V
H
L
K
S
F
T
E
Q
L
R
K
Rat
Rattus norvegicus
Q9QZ81
860
97300
S470
C
T
E
V
H
L
K
S
F
T
E
Q
L
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513588
873
98974
S483
C
T
E
V
H
L
K
S
F
T
E
Q
L
R
K
Chicken
Gallus gallus
Q5ZLG4
860
97253
G470
C
R
E
E
I
L
K
G
F
T
D
Q
L
R
K
Frog
Xenopus laevis
Q6DCX2
862
97626
T472
C
T
E
V
H
L
K
T
F
T
E
Q
L
R
K
Zebra Danio
Brachydanio rerio
A3KPK0
860
97313
G470
C
R
E
E
V
L
K
G
F
T
D
Q
L
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUQ5
1214
136831
G841
Y
T
Q
L
N
D
F
G
N
L
I
I
S
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34681
1040
115397
T608
R
D
Q
T
S
L
Q
T
F
C
Q
S
L
T
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
T621
V
Q
D
N
L
A
R
T
F
C
Q
E
L
A
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
80.2
95.3
N.A.
98.9
99
N.A.
97.1
79.7
96.1
79.4
N.A.
22.4
N.A.
33.4
N.A.
Protein Similarity:
100
94.6
81
95.3
N.A.
99
99.3
N.A.
97.5
89.3
98.2
89.4
N.A.
36.4
N.A.
51.5
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
66.6
93.3
66.6
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
73.3
100
73.3
N.A.
33.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% A
% Cys:
70
0
0
0
0
0
0
0
0
16
8
0
8
0
0
% C
% Asp:
8
8
8
0
0
8
0
0
0
0
16
0
0
0
0
% D
% Glu:
0
0
70
16
0
0
0
0
0
0
54
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
85
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
31
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
8
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
70
0
0
0
0
0
0
8
70
% K
% Leu:
0
0
0
8
8
77
0
0
0
8
0
0
85
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
8
16
0
0
0
16
0
8
0
16
70
0
8
8
% Q
% Arg:
8
16
0
0
0
0
8
0
0
0
0
0
0
70
0
% R
% Ser:
0
0
0
0
8
0
0
47
0
0
0
8
8
0
0
% S
% Thr:
0
62
0
8
0
0
0
24
0
70
0
0
0
8
0
% T
% Val:
8
0
0
54
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _