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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAV3 All Species: 31.82
Human Site: T319 Identified Species: 63.64
UniProt: Q9UKW4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKW4 NP_001073343.1 847 97776 T319 R A N N G K F T L R D L L V V
Chimpanzee Pan troglodytes XP_001150955 788 91255 H290 L L Q E L V K H T Q E A M E K
Rhesus Macaque Macaca mulatta XP_001083337 847 97793 T319 R A N N G K F T L R D L L V V
Dog Lupus familis XP_537047 831 95340 T303 R A N N G K F T L R D L L V V
Cat Felis silvestris
Mouse Mus musculus Q9R0C8 847 97949 T319 R A N N G K F T L R D L L V V
Rat Rattus norvegicus P54100 843 97935 T321 R A N N G R F T L R D L L M V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505586 846 97900 K319 K V Q E G K F K L Q D L L V V
Chicken Gallus gallus NP_996745 846 97797 T319 R A N N G K F T L R D L L V V
Frog Xenopus laevis NP_001086991 845 97765 S323 R A N N G R F S L R D L L M V
Zebra Danio Brachydanio rerio NP_001119865 822 94769 T313 R A N N G K F T L R D L L V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NHV9 793 91337 L293 V K M A Q V F L D F R E P F L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q45FX5 1007 113536 M385 Q G N C K F G M N D L L C V P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.5 98.8 90.7 N.A. 95.4 59.5 N.A. 51.8 86.1 58 68.8 N.A. 30.8 N.A. 26.4 N.A.
Protein Similarity: 100 70.3 99.1 93.2 N.A. 97.1 75.5 N.A. 70.4 93.1 73 80.6 N.A. 50.7 N.A. 44.9 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 86.6 N.A. 60 100 80 100 N.A. 6.6 N.A. 20 N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 73.3 100 100 100 N.A. 13.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 67 0 9 0 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 9 75 0 0 0 0 % D
% Glu: 0 0 0 17 0 0 0 0 0 0 9 9 0 9 0 % E
% Phe: 0 0 0 0 0 9 84 0 0 9 0 0 0 9 0 % F
% Gly: 0 9 0 0 75 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 9 0 0 9 59 9 9 0 0 0 0 0 0 9 % K
% Leu: 9 9 0 0 9 0 0 9 75 0 9 84 75 0 9 % L
% Met: 0 0 9 0 0 0 0 9 0 0 0 0 9 17 0 % M
% Asn: 0 0 75 67 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % P
% Gln: 9 0 17 0 9 0 0 0 0 17 0 0 0 0 0 % Q
% Arg: 67 0 0 0 0 17 0 0 0 67 9 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 59 9 0 0 0 0 0 0 % T
% Val: 9 9 0 0 0 17 0 0 0 0 0 0 0 67 75 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _