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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP50 All Species: 10.3
Human Site: S223 Identified Species: 18.89
UniProt: Q9UKX7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKX7 NP_009103.2 468 50144 S223 A A E T Q S P S L F G S T K L
Chimpanzee Pan troglodytes XP_001135221 468 50124 S223 A A E T Q S P S L F G S T K L
Rhesus Macaque Macaca mulatta XP_001109545 468 50114 P223 T A A E T Q S P S L F G S T K
Dog Lupus familis XP_531700 476 50812 K216 S S E S E T N K M P L A T Q S
Cat Felis silvestris
Mouse Mus musculus Q9JIH2 466 49477 P222 A T A G M E P P S L F G S T K
Rat Rattus norvegicus O08587 467 49799 P223 A T A A M E P P S L F G S T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505805 474 48783 G229 D S G S E S E G S R K P S G P
Chicken Gallus gallus NP_001012559 468 50089 S227 T P G T Q S A S T F G N S K L
Frog Xenopus laevis NP_001089033 436 46689 S214 K T I P N L P S I K A D S I A
Zebra Danio Brachydanio rerio NP_963874 421 44559 G199 G A A D E T P G K P L A S C A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610355 564 59416 K262 R S Q E P V A K V S R A S S P
Honey Bee Apis mellifera XP_394340 527 58017 T218 S S D N K E S T N T E K K L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32499 720 77862 K338 E N S T S N S K P E K S S D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 97 82.5 N.A. 77.9 78.8 N.A. 71 72.2 58.9 53.4 N.A. 32 33.7 N.A. N.A.
Protein Similarity: 100 99.3 98 87.8 N.A. 86.1 86.9 N.A. 79.1 80.5 71.1 66.8 N.A. 47.7 49.9 N.A. N.A.
P-Site Identity: 100 100 6.6 13.3 N.A. 13.3 13.3 N.A. 6.6 53.3 13.3 13.3 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 100 13.3 66.6 N.A. 20 20 N.A. 33.3 66.6 26.6 40 N.A. 33.3 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 31 31 8 0 0 16 0 0 0 8 24 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 0 8 8 0 0 0 0 0 0 0 8 0 8 0 % D
% Glu: 8 0 24 16 24 24 8 0 0 8 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 24 24 0 0 0 0 % F
% Gly: 8 0 16 8 0 0 0 16 0 0 24 24 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 8 0 0 0 0 8 0 % I
% Lys: 8 0 0 0 8 0 0 24 8 8 16 8 8 24 24 % K
% Leu: 0 0 0 0 0 8 0 0 16 24 16 0 0 8 24 % L
% Met: 0 0 0 0 16 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 8 8 8 0 8 0 0 8 0 0 0 % N
% Pro: 0 8 0 8 8 0 47 24 8 16 0 8 0 0 16 % P
% Gln: 0 0 8 0 24 8 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % R
% Ser: 16 31 8 16 8 31 24 31 31 8 0 24 70 8 16 % S
% Thr: 16 24 0 31 8 16 0 8 8 8 0 0 24 24 0 % T
% Val: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _