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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP50 All Species: 12.42
Human Site: S263 Identified Species: 22.78
UniProt: Q9UKX7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKX7 NP_009103.2 468 50144 S263 E K K T D P S S L G A T S A S
Chimpanzee Pan troglodytes XP_001135221 468 50124 S263 E K K T D P S S L G A T S A S
Rhesus Macaque Macaca mulatta XP_001109545 468 50114 S263 S E K K T D P S L G A T S A S
Dog Lupus familis XP_531700 476 50812 S256 S E K K T D L S V G A A S A S
Cat Felis silvestris
Mouse Mus musculus Q9JIH2 466 49477 Q262 E K K S D A A Q G A T S A S F
Rat Rattus norvegicus O08587 467 49799 Q263 E K K S D A A Q G A T S A S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505805 474 48783 K269 A D T G A E K K E E P V A G S
Chicken Gallus gallus NP_001012559 468 50089 A267 K R D P S I G A T S T V S F N
Frog Xenopus laevis NP_001089033 436 46689 D254 F N F G Q K V D S S T L S L I
Zebra Danio Brachydanio rerio NP_963874 421 44559 K239 V S F N F G K K V D S S V L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610355 564 59416 S302 K P N C T I T S G G T T T T T
Honey Bee Apis mellifera XP_394340 527 58017 K258 G N I S A G S K S I F R K S E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32499 720 77862 K378 F G V P N S S K N E T S K P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 97 82.5 N.A. 77.9 78.8 N.A. 71 72.2 58.9 53.4 N.A. 32 33.7 N.A. N.A.
Protein Similarity: 100 99.3 98 87.8 N.A. 86.1 86.9 N.A. 79.1 80.5 71.1 66.8 N.A. 47.7 49.9 N.A. N.A.
P-Site Identity: 100 100 60 46.6 N.A. 26.6 26.6 N.A. 6.6 6.6 6.6 0 N.A. 20 6.6 N.A. N.A.
P-Site Similarity: 100 100 66.6 60 N.A. 60 60 N.A. 13.3 33.3 6.6 20 N.A. 46.6 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 16 16 16 8 0 16 31 8 24 31 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 31 16 0 8 0 8 0 0 0 0 0 % D
% Glu: 31 16 0 0 0 8 0 0 8 16 0 0 0 0 8 % E
% Phe: 16 0 16 0 8 0 0 0 0 0 8 0 0 8 16 % F
% Gly: 8 8 0 16 0 16 8 0 24 39 0 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 16 0 0 0 8 0 0 0 0 8 % I
% Lys: 16 31 47 16 0 8 16 31 0 0 0 0 16 0 0 % K
% Leu: 0 0 0 0 0 0 8 0 24 0 0 8 0 16 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 16 8 8 8 0 0 0 8 0 0 0 0 0 8 % N
% Pro: 0 8 0 16 0 16 8 0 0 0 8 0 0 8 0 % P
% Gln: 0 0 0 0 8 0 0 16 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 16 8 0 24 8 8 31 39 16 16 8 31 47 24 39 % S
% Thr: 0 0 8 16 24 0 8 0 8 0 47 31 8 8 8 % T
% Val: 8 0 8 0 0 0 8 0 16 0 0 16 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _