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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP50 All Species: 13.64
Human Site: T291 Identified Species: 25
UniProt: Q9UKX7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKX7 NP_009103.2 468 50144 T291 S L S S V P L T G F S F S P G
Chimpanzee Pan troglodytes XP_001135221 468 50124 T291 S L S S V P L T G F S F S P G
Rhesus Macaque Macaca mulatta XP_001109545 468 50114 T291 S L S S V P L T G F S F S P G
Dog Lupus familis XP_531700 476 50812 T284 S L N S G P L T G F S F S S G
Cat Felis silvestris
Mouse Mus musculus Q9JIH2 466 49477 G290 L S S G S L T G F S F S A G S
Rat Rattus norvegicus O08587 467 49799 G291 L S S G S L T G F S F S P G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505805 474 48783 P297 A L G S G P L P S F S F S P G
Chicken Gallus gallus NP_001012559 468 50089 F295 G S G T R S S F S F S P G N P
Frog Xenopus laevis NP_001089033 436 46689 N282 A S S L F G K N N A S T A S S
Zebra Danio Brachydanio rerio NP_963874 421 44559 V267 S S S S S S A V F G S A V S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610355 564 59416 S330 T A P V P S S S S I F S L T A
Honey Bee Apis mellifera XP_394340 527 58017 K286 D Q S S D I Q K S V F G N I D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32499 720 77862 N406 S Q E D D N N N V E K P S S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 97 82.5 N.A. 77.9 78.8 N.A. 71 72.2 58.9 53.4 N.A. 32 33.7 N.A. N.A.
Protein Similarity: 100 99.3 98 87.8 N.A. 86.1 86.9 N.A. 79.1 80.5 71.1 66.8 N.A. 47.7 49.9 N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 6.6 6.6 N.A. 66.6 13.3 13.3 26.6 N.A. 0 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 13.3 6.6 N.A. 73.3 20 26.6 26.6 N.A. 13.3 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 0 0 0 8 0 0 8 0 8 16 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 16 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 8 24 47 31 39 0 0 0 % F
% Gly: 8 0 16 16 16 8 0 16 31 8 0 8 8 16 39 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 8 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 8 8 0 0 8 0 0 0 8 % K
% Leu: 16 39 0 8 0 16 39 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 8 16 8 0 0 0 8 8 8 % N
% Pro: 0 0 8 0 8 39 0 8 0 0 0 16 8 31 8 % P
% Gln: 0 16 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 47 39 62 54 24 24 16 8 31 16 62 24 47 31 24 % S
% Thr: 8 0 0 8 0 0 16 31 0 0 0 8 0 8 0 % T
% Val: 0 0 0 8 24 0 0 8 8 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _