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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DSE All Species: 31.82
Human Site: S263 Identified Species: 77.78
UniProt: Q9UL01 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UL01 NP_001074445.1 958 109773 S263 Y E G V A Y G S Y T T R S L F
Chimpanzee Pan troglodytes XP_518705 958 109820 S263 Y E G V A Y G S Y T T R S L F
Rhesus Macaque Macaca mulatta XP_001111719 958 109947 S263 Y E G V A Y G S Y T T R S L F
Dog Lupus familis XP_533477 959 110008 S263 Y E G V A Y G S Y T T R S L F
Cat Felis silvestris
Mouse Mus musculus Q8BLI4 958 109736 S263 Y E G V A Y G S Y T T R S L F
Rat Rattus norvegicus NP_001102403 958 109877 S263 Y E G V A Y G S Y T T R S L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520171 1229 137870 Y282 E G V A Y G S Y T A K S I T Q
Chicken Gallus gallus XP_419777 985 112953 S289 Y E G V A Y G S Y T T R S L F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001025396 949 107929 T265 Y E G V A Y G T Y T T R S L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787972 1183 135365 M259 G S Y T S R S M M Q Y I F L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.8 96.1 N.A. 93.8 94 N.A. 35.3 82.8 N.A. 65.3 N.A. N.A. N.A. N.A. 32.1
Protein Similarity: 100 99.3 99.4 97.9 N.A. 97.2 97.4 N.A. 49.8 89.3 N.A. 78.8 N.A. N.A. N.A. N.A. 48.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 100 N.A. 93.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 100 N.A. 100 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 80 0 0 0 0 10 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 80 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 80 % F
% Gly: 10 10 80 0 0 10 80 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 90 0 % L
% Met: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 80 0 0 0 % R
% Ser: 0 10 0 0 10 0 20 70 0 0 0 10 80 0 0 % S
% Thr: 0 0 0 10 0 0 0 10 10 80 80 0 0 10 0 % T
% Val: 0 0 10 80 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 80 0 10 0 10 80 0 10 80 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _