KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2C1
All Species:
13.64
Human Site:
Y92
Identified Species:
25
UniProt:
Q9UL18
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UL18
NP_036331.1
857
97214
Y92
F
G
D
R
K
P
V
Y
D
G
K
K
N
I
Y
Chimpanzee
Pan troglodytes
XP_001167349
817
92830
K82
V
T
I
P
G
E
G
K
D
R
I
F
K
V
S
Rhesus Macaque
Macaca mulatta
XP_001100725
1053
117937
F286
F
G
D
R
K
P
V
F
D
G
R
K
N
L
Y
Dog
Lupus familis
XP_532563
1037
115859
Y272
F
G
D
R
K
P
V
Y
D
G
K
K
N
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8CJG1
857
97083
Y92
F
G
D
R
K
P
V
Y
D
G
K
E
N
I
Y
Rat
Rattus norvegicus
Q9QZ81
860
97300
F95
F
G
D
R
K
P
V
F
D
G
R
K
N
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510209
1055
118422
Y288
F
G
D
R
K
P
V
Y
D
G
K
K
N
I
Y
Chicken
Gallus gallus
Q5ZLG4
860
97253
A95
G
K
R
S
L
Y
T
A
N
P
L
P
V
A
T
Frog
Xenopus laevis
Q6DCX2
862
97626
D97
G
D
R
K
P
V
F
D
G
R
K
N
L
Y
T
Zebra Danio
Brachydanio rerio
A3KPK0
860
97313
A95
G
K
K
S
L
Y
T
A
Q
P
L
P
V
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUQ5
1214
136831
D468
G
G
A
V
L
A
Y
D
G
K
A
S
C
Y
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34681
1040
115397
H164
A
L
A
Y
D
G
A
H
Q
L
Y
T
V
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
S253
P
A
Y
D
G
R
K
S
L
Y
T
A
G
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
66.8
82.6
N.A.
99.5
82.3
N.A.
75.2
84.5
82
84.7
N.A.
23.2
N.A.
32.6
N.A.
Protein Similarity:
100
94.1
74.8
82.6
N.A.
99.7
91.2
N.A.
76.7
91.6
90.5
92
N.A.
37.1
N.A.
51.1
N.A.
P-Site Identity:
100
6.6
80
100
N.A.
93.3
80
N.A.
100
0
6.6
0
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
6.6
13.3
0
N.A.
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
16
0
0
8
8
16
0
0
8
8
0
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
47
8
8
0
0
16
54
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% E
% Phe:
47
0
0
0
0
0
8
16
0
0
0
8
0
0
0
% F
% Gly:
31
54
0
0
16
8
8
0
16
47
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
8
0
0
31
0
% I
% Lys:
0
16
8
8
47
0
8
8
0
8
39
39
8
0
0
% K
% Leu:
0
8
0
0
24
0
0
0
8
8
16
0
8
16
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
8
47
0
0
% N
% Pro:
8
0
0
8
8
47
0
0
0
16
0
16
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% Q
% Arg:
0
0
16
47
0
8
0
0
0
16
16
0
0
0
8
% R
% Ser:
0
0
0
16
0
0
0
8
0
0
0
8
0
0
24
% S
% Thr:
0
8
0
0
0
0
16
0
0
0
8
8
0
0
16
% T
% Val:
8
0
0
8
0
8
47
0
0
0
0
0
24
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
16
8
31
0
8
8
0
0
16
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _