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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCN2
All Species:
7.88
Human Site:
S146
Identified Species:
24.76
UniProt:
Q9UL51
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UL51
NP_001185.3
889
96950
S146
G
P
A
E
E
A
G
S
E
E
A
G
P
A
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115891
777
86237
A85
E
R
V
K
S
A
G
A
W
I
I
H
P
Y
S
Dog
Lupus familis
XP_855233
837
92350
R95
T
C
G
V
R
V
P
R
P
R
S
A
S
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
O88703
863
94703
S119
S
A
A
E
E
A
G
S
E
E
A
G
P
A
G
Rat
Rattus norvegicus
Q9JKA9
863
94902
S119
A
A
A
E
E
A
G
S
E
E
A
G
P
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425050
1188
129247
G131
D
K
S
P
S
G
S
G
E
T
Q
G
L
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685414
901
101015
Q93
F
S
K
S
E
D
G
Q
I
T
A
E
D
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24278
665
75805
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.5
79.1
N.A.
91.7
91.4
N.A.
N.A.
49.6
N.A.
70.8
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
66.8
82
N.A.
92.8
92.3
N.A.
N.A.
56.8
N.A.
76.8
N.A.
37.9
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
20
0
N.A.
86.6
86.6
N.A.
N.A.
13.3
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
33.3
13.3
N.A.
86.6
86.6
N.A.
N.A.
20
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
25
38
0
0
50
0
13
0
0
50
13
0
38
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
13
0
0
0
0
0
0
13
0
0
% D
% Glu:
13
0
0
38
50
0
0
0
50
38
0
13
0
0
13
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
13
0
0
13
63
13
0
0
0
50
0
13
38
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
13
13
0
0
0
0
% I
% Lys:
0
13
13
13
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
13
0
0
13
0
13
0
0
0
50
13
0
% P
% Gln:
0
0
0
0
0
0
0
13
0
0
13
0
0
0
0
% Q
% Arg:
0
13
0
0
13
0
0
13
0
13
0
0
0
0
0
% R
% Ser:
13
13
13
13
25
0
13
38
0
0
13
0
13
13
13
% S
% Thr:
13
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% T
% Val:
0
0
13
13
0
13
0
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _