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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKLN1
All Species:
34.55
Human Site:
S356
Identified Species:
63.33
UniProt:
Q9UL63
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UL63
NP_001138826.1
735
84768
S356
S
S
V
R
N
S
K
S
L
K
S
D
F
Y
R
Chimpanzee
Pan troglodytes
XP_001135240
643
74481
R271
S
L
K
S
D
F
Y
R
Y
D
I
D
T
N
T
Rhesus Macaque
Macaca mulatta
XP_001098817
735
84767
S356
S
S
V
R
N
S
K
S
L
K
S
D
F
Y
R
Dog
Lupus familis
XP_850354
251
28798
Cat
Felis silvestris
Mouse
Mus musculus
O89050
735
84859
S356
S
S
V
R
N
S
K
S
L
K
S
D
F
Y
R
Rat
Rattus norvegicus
Q99PV3
735
84815
S356
S
S
V
R
N
S
K
S
L
K
S
D
F
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511026
709
82133
S330
S
S
V
R
N
S
K
S
L
K
S
D
F
Y
R
Chicken
Gallus gallus
NP_001025944
733
84525
S354
S
S
V
R
N
S
K
S
L
K
S
D
F
Y
R
Frog
Xenopus laevis
NP_001087072
727
84623
S348
S
S
V
R
N
S
K
S
L
K
S
D
F
Y
C
Zebra Danio
Brachydanio rerio
NP_997859
729
84358
S350
S
S
V
R
N
S
K
S
L
K
S
D
F
Y
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610801
853
97490
Y384
N
S
I
R
T
S
D
Y
I
K
S
D
F
Y
L
Honey Bee
Apis mellifera
XP_624921
760
87304
N363
A
E
Y
R
T
P
E
N
L
K
S
D
F
F
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793226
1390
161226
P358
Q
T
M
R
N
T
T
P
L
K
S
D
F
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
99.7
33.8
N.A.
99.1
99.3
N.A.
94.1
96.1
89.9
89.1
N.A.
42.3
54
N.A.
32.6
Protein Similarity:
100
87.4
100
34.1
N.A.
99.5
99.8
N.A.
95.7
98.3
95
95.2
N.A.
61.3
70.9
N.A.
41.9
P-Site Identity:
100
13.3
100
0
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
53.3
40
N.A.
53.3
P-Site Similarity:
100
20
100
0
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
73.3
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% C
% Asp:
0
0
0
0
8
0
8
0
0
8
0
93
0
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
85
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
62
0
0
85
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
77
0
0
0
0
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
70
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
85
0
0
0
8
0
0
0
0
0
0
47
% R
% Ser:
70
70
0
8
0
70
0
62
0
0
85
0
0
0
0
% S
% Thr:
0
8
0
0
16
8
8
0
0
0
0
0
8
0
8
% T
% Val:
0
0
62
0
0
0
0
0
0
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
8
8
0
0
0
0
77
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _