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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKLN1
All Species:
40.3
Human Site:
S627
Identified Species:
73.89
UniProt:
Q9UL63
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UL63
NP_001138826.1
735
84768
S627
S
L
K
L
C
R
P
S
K
D
Y
L
L
R
H
Chimpanzee
Pan troglodytes
XP_001135240
643
74481
Y538
L
C
R
P
S
K
D
Y
L
L
R
H
C
K
Y
Rhesus Macaque
Macaca mulatta
XP_001098817
735
84767
S627
S
L
K
L
C
R
P
S
K
D
Y
L
L
R
H
Dog
Lupus familis
XP_850354
251
28798
E146
N
T
W
M
L
L
S
E
D
T
A
A
D
G
G
Cat
Felis silvestris
Mouse
Mus musculus
O89050
735
84859
S627
S
L
K
L
C
R
P
S
K
D
Y
L
L
R
H
Rat
Rattus norvegicus
Q99PV3
735
84815
S627
S
L
K
L
C
R
P
S
K
D
Y
L
L
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511026
709
82133
S601
S
L
K
L
C
R
P
S
K
E
Y
L
L
R
H
Chicken
Gallus gallus
NP_001025944
733
84525
S625
S
L
K
L
C
R
P
S
K
E
Y
L
L
R
H
Frog
Xenopus laevis
NP_001087072
727
84623
S619
S
L
K
L
C
R
P
S
K
E
Y
L
L
R
H
Zebra Danio
Brachydanio rerio
NP_997859
729
84358
S621
S
L
K
L
C
R
P
S
K
E
Y
L
L
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610801
853
97490
K679
L
L
C
L
E
K
P
K
R
E
E
I
L
K
H
Honey Bee
Apis mellifera
XP_624921
760
87304
S632
Q
L
K
L
C
R
P
S
H
E
Q
I
L
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793226
1390
161226
T644
S
L
E
L
C
R
P
T
K
E
E
L
V
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
99.7
33.8
N.A.
99.1
99.3
N.A.
94.1
96.1
89.9
89.1
N.A.
42.3
54
N.A.
32.6
Protein Similarity:
100
87.4
100
34.1
N.A.
99.5
99.8
N.A.
95.7
98.3
95
95.2
N.A.
61.3
70.9
N.A.
41.9
P-Site Identity:
100
0
100
0
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
33.3
53.3
N.A.
60
P-Site Similarity:
100
26.6
100
13.3
N.A.
100
100
N.A.
100
100
100
100
N.A.
66.6
73.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% A
% Cys:
0
8
8
0
77
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
31
0
0
8
0
0
% D
% Glu:
0
0
8
0
8
0
0
8
0
54
16
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
70
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% I
% Lys:
0
0
70
0
0
16
0
8
70
0
0
0
0
24
8
% K
% Leu:
16
85
0
85
8
8
0
0
8
8
0
70
77
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
85
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
8
0
0
77
0
0
8
0
8
0
0
70
8
% R
% Ser:
70
0
0
0
8
0
8
70
0
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
62
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _