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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNPEP All Species: 27.88
Human Site: S285 Identified Species: 51.11
UniProt: Q9ULA0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULA0 NP_036232.2 475 52428 S285 D S C A G P G S L A T E P H V
Chimpanzee Pan troglodytes XP_001163232 485 53450 S295 D S C T G P G S L A T E P H V
Rhesus Macaque Macaca mulatta XP_001103498 493 54434 S303 D S C A G P G S L A M E P H V
Dog Lupus familis XP_536081 475 52296 S285 D S C A A P A S L S S E P H V
Cat Felis silvestris
Mouse Mus musculus Q9Z2W0 473 52148 S283 D S C A S P A S L A R D P H V
Rat Rattus norvegicus NP_001020050 475 52537 S285 D S C A S P A S L A R E P H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012937 473 51842 S283 I D S C T V P S L S Q E P N V
Frog Xenopus laevis NP_001085525 479 53017 S289 G S C E S P S S L A S D P N V
Zebra Danio Brachydanio rerio NP_956447 469 51212 S279 V D S S T P D S L A K D P N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19087 470 51138 E282 L L E S L T G E S F K N D P Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002318119 483 53225 D291 D A T S T E S D L K D E S G V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200824 477 52407 D285 D A T S S G S D L E D E S G I
Baker's Yeast Sacchar. cerevisiae P38821 490 54155 D294 L A A D T E I D R E S G I R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 94.3 92.6 N.A. 89.2 90.1 N.A. N.A. 77 70.3 69.6 N.A. N.A. N.A. 49.8 N.A.
Protein Similarity: 100 97.5 95.7 96.8 N.A. 94.3 95.1 N.A. N.A. 88.2 83 82.9 N.A. N.A. N.A. 67.1 N.A.
P-Site Identity: 100 93.3 93.3 73.3 N.A. 73.3 80 N.A. N.A. 33.3 53.3 40 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 80 80 N.A. N.A. 46.6 73.3 60 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: 50.1 N.A. N.A. 50.7 43.4 N.A.
Protein Similarity: 68.5 N.A. N.A. 69.6 61.4 N.A.
P-Site Identity: 26.6 N.A. N.A. 20 0 N.A.
P-Site Similarity: 40 N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 8 39 8 0 24 0 0 54 0 0 0 0 0 % A
% Cys: 0 0 54 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 62 16 0 8 0 0 8 24 0 0 16 24 8 0 0 % D
% Glu: 0 0 8 8 0 16 0 8 0 16 0 62 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 8 0 0 0 24 8 31 0 0 0 0 8 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 % H
% Ile: 8 0 0 0 0 0 8 0 0 0 0 0 8 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 16 0 0 0 0 % K
% Leu: 16 8 0 0 8 0 0 0 85 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 24 0 % N
% Pro: 0 0 0 0 0 62 8 0 0 0 0 0 70 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 16 0 0 8 0 % R
% Ser: 0 54 16 31 31 0 24 70 8 16 24 0 16 0 0 % S
% Thr: 0 0 16 8 31 8 0 0 0 0 16 0 0 0 0 % T
% Val: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 77 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _