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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCTS1 All Species: 53.64
Human Site: Y169 Identified Species: 84.29
UniProt: Q9ULC4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULC4 NP_054779.1 181 20555 Y169 I G I E N I H Y L N D G L W H
Chimpanzee Pan troglodytes XP_001137138 138 15505 Y126 I G I E N I H Y L N D G L W H
Rhesus Macaque Macaca mulatta XP_001086431 181 20524 Y169 I G I E N I H Y L N D G L W H
Dog Lupus familis XP_544278 338 37789 Y326 I G I E N I H Y L N D G L W H
Cat Felis silvestris
Mouse Mus musculus Q9DB27 181 20537 Y169 I G I E N I H Y L N D G L W H
Rat Rattus norvegicus Q4G009 182 20532 Y170 I G I E N I H Y L N D G L W H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510152 199 22096 Y187 I G I E N I H Y L N D G L W H
Chicken Gallus gallus Q5ZI42 181 20553 Y169 I G I E N I H Y L N D G L W H
Frog Xenopus laevis Q5PPY1 181 20512 Y169 I G I E N I H Y L N D G L W H
Zebra Danio Brachydanio rerio Q7ZV34 181 20591 Y169 I G I E N V H Y L N D G L W H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572288 182 20329 F170 I G I E T Y H F L N D G L W K
Honey Bee Apis mellifera XP_001120413 182 20404 Y170 I G I E N C H Y L N D G L W Q
Nematode Worm Caenorhab. elegans NP_741412 185 20752 Y171 N G I E N L H Y L N D G L W H
Sea Urchin Strong. purpuratus XP_780147 183 20265 Y171 I G I E N I H Y L N D G L W H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P89886 181 20259 H170 H S I E L I H H L G D P L W N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.2 98.9 52.3 N.A. 99.4 97.8 N.A. 86.9 97.2 96.6 93.9 N.A. 59.3 68.1 62.1 65
Protein Similarity: 100 76.2 99.4 53.5 N.A. 100 98.9 N.A. 89.4 98.9 98.9 97.2 N.A. 79.1 82.9 80 79.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 73.3 86.6 86.6 100
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 80 86.6 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 47.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 72.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % D
% Glu: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 94 0 0 0 0 0 0 0 7 0 94 0 0 0 % G
% His: 7 0 0 0 0 0 100 7 0 0 0 0 0 0 80 % H
% Ile: 87 0 100 0 0 74 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 0 0 0 0 7 7 0 0 100 0 0 0 100 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 87 0 0 0 0 94 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % W
% Tyr: 0 0 0 0 0 7 0 87 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _