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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACSL5 All Species: 6.97
Human Site: S251 Identified Species: 13.94
UniProt: Q9ULC5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.45
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULC5 NP_976313.1 683 75991 S251 F R K P V P P S P E D L S V I
Chimpanzee Pan troglodytes XP_001145825 723 80445 S291 F R K P V P P S P E D L S V I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535014 683 76216 R251 F R K P V P P R P E D L S I I
Cat Felis silvestris
Mouse Mus musculus Q8JZR0 683 76188 K251 F K K P V P P K P E D L S V I
Rat Rattus norvegicus O88813 683 76386 N251 F K K P M P P N P E D L S V I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513244 684 75491 K251 F K K P V P P K P K D L C L I
Chicken Gallus gallus Q5ZKR7 763 84188 K271 R E I I E S Q K P N Q C C T L
Frog Xenopus laevis Q7ZYC4 739 81601 K277 D Q I I S S Q K P N Q C C T L
Zebra Danio Brachydanio rerio NP_001004599 681 75299 K251 H H R P V P P K P E D L S I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3S9 666 73592 V233 L V Y T S G T V G M P K G V M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84P24 566 61938 E154 G L A F T S T E N V E K L S S
Baker's Yeast Sacchar. cerevisiae P39518 744 83419 T290 K I P A I P P T P D S L Y T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 N.A. 83.7 N.A. 81.4 81.1 N.A. 77.1 23.3 25.9 66.6 N.A. 27.6 N.A. N.A. N.A.
Protein Similarity: 100 93.7 N.A. 91.8 N.A. 91.9 92.2 N.A. 88 43.7 45.7 81.5 N.A. 46.5 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 86.6 N.A. 86.6 80 N.A. 66.6 6.6 6.6 66.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 100 N.A. 86.6 13.3 20 80 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.4 32.3 N.A.
Protein Similarity: N.A. N.A. N.A. 41.5 50.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 17 25 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 9 59 0 0 0 0 % D
% Glu: 0 9 0 0 9 0 0 9 0 50 9 0 0 0 0 % E
% Phe: 50 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 9 0 0 9 0 0 0 9 0 0 % G
% His: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 17 17 9 0 0 0 0 0 0 0 0 17 67 % I
% Lys: 9 25 50 0 0 0 0 42 0 9 0 17 0 0 0 % K
% Leu: 9 9 0 0 0 0 0 0 0 0 0 67 9 9 17 % L
% Met: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 9 9 17 0 0 0 0 0 % N
% Pro: 0 0 9 59 0 67 67 0 84 0 9 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 17 0 0 0 17 0 0 0 0 % Q
% Arg: 9 25 9 0 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 17 25 0 17 0 0 9 0 50 9 9 % S
% Thr: 0 0 0 9 9 0 17 9 0 0 0 0 0 25 0 % T
% Val: 0 9 0 0 50 0 0 9 0 9 0 0 0 42 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _