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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACSL5 All Species: 27.58
Human Site: S580 Identified Species: 55.15
UniProt: Q9ULC5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULC5 NP_976313.1 683 75991 S580 V H G E S L R S S L V G V V V
Chimpanzee Pan troglodytes XP_001145825 723 80445 S620 V H G E S L R S S L V G V V V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535014 683 76216 S580 V H G D S L R S S L V G V V V
Cat Felis silvestris
Mouse Mus musculus Q8JZR0 683 76188 S580 V H G E S L R S F L I G V V V
Rat Rattus norvegicus O88813 683 76386 S580 V H G E S L R S F L I G V V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513244 684 75491 S580 V H G E S L R S T L V G V V V
Chicken Gallus gallus Q5ZKR7 763 84188 A604 A M L V G D K A K F L A M L L
Frog Xenopus laevis Q7ZYC4 739 81601 A625 T L K C N V N A D T G E P E D
Zebra Danio Brachydanio rerio NP_001004599 681 75299 S580 V H G E S L Q S S L V A I V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3S9 666 73592 T557 K Y L T V L I T L K T E V D K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84P24 566 61938 D473 G F Q I A P A D L E A V L V S
Baker's Yeast Sacchar. cerevisiae P39518 744 83419 K629 F V F G D P L K T F L V G I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 N.A. 83.7 N.A. 81.4 81.1 N.A. 77.1 23.3 25.9 66.6 N.A. 27.6 N.A. N.A. N.A.
Protein Similarity: 100 93.7 N.A. 91.8 N.A. 91.9 92.2 N.A. 88 43.7 45.7 81.5 N.A. 46.5 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 86.6 N.A. 93.3 0 0 80 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 100 40 20 93.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.4 32.3 N.A.
Protein Similarity: N.A. N.A. N.A. 41.5 50.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 9 17 0 0 9 17 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 9 9 0 9 9 0 0 0 0 9 9 % D
% Glu: 0 0 0 50 0 0 0 0 0 9 0 17 0 9 0 % E
% Phe: 9 9 9 0 0 0 0 0 17 17 0 0 0 0 0 % F
% Gly: 9 0 59 9 9 0 0 0 0 0 9 50 9 0 0 % G
% His: 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 9 0 0 0 17 0 9 9 0 % I
% Lys: 9 0 9 0 0 0 9 9 9 9 0 0 0 0 9 % K
% Leu: 0 9 17 0 0 67 9 0 17 59 17 0 9 9 9 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 17 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 59 0 0 59 34 0 0 0 0 0 9 % S
% Thr: 9 0 0 9 0 0 0 9 17 9 9 0 0 0 0 % T
% Val: 59 9 0 9 9 9 0 0 0 0 42 17 59 67 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _