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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNH3
All Species:
11.52
Human Site:
S422
Identified Species:
28.15
UniProt:
Q9ULD8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULD8
NP_036416.1
1083
117129
S422
R
R
P
A
G
G
N
S
S
G
Q
S
D
N
C
Chimpanzee
Pan troglodytes
XP_509046
1083
117183
S422
R
R
P
A
G
G
N
S
S
G
Q
S
D
N
C
Rhesus Macaque
Macaca mulatta
XP_001109598
1083
117285
S422
R
R
P
A
G
G
N
S
S
G
Q
S
D
N
C
Dog
Lupus familis
XP_543682
1116
119872
S450
R
G
P
A
G
N
S
S
G
Q
K
D
N
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVJ0
1087
117519
Q425
D
G
G
N
S
S
G
Q
S
E
N
C
S
S
S
Rat
Rattus norvegicus
O89047
1087
117562
Q425
D
G
G
N
S
S
G
Q
S
E
N
C
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508200
1155
129668
W439
R
E
E
N
S
L
T
W
E
V
G
W
L
P
E
Chicken
Gallus gallus
Q9PT84
526
59775
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919436
1190
130720
L458
P
V
W
N
S
S
Q
L
N
S
T
G
T
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02280
1174
126352
L410
Q
Y
S
W
L
W
K
L
A
N
V
T
Q
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
89.7
N.A.
95.4
95.5
N.A.
45.7
22.4
N.A.
47.6
N.A.
30.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.6
91.7
N.A.
96.4
96.5
N.A.
60
32.7
N.A.
60
N.A.
48.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
33.3
N.A.
6.6
6.6
N.A.
6.6
0
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
13.3
13.3
N.A.
6.6
0
N.A.
6.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
40
0
0
0
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
20
0
10
30
% C
% Asp:
20
0
0
0
0
0
0
0
0
0
0
10
30
0
0
% D
% Glu:
0
10
10
0
0
0
0
0
10
20
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
30
20
0
40
30
20
0
10
30
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
10
10
0
20
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
40
0
10
30
0
10
10
20
0
10
30
0
% N
% Pro:
10
0
40
0
0
0
0
0
0
0
0
0
0
10
20
% P
% Gln:
10
0
0
0
0
0
10
20
0
10
30
0
10
0
0
% Q
% Arg:
50
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
40
30
10
40
50
10
0
30
20
30
30
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
10
10
10
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
10
10
0
10
0
10
0
0
0
10
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _