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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WWC3
All Species:
15.45
Human Site:
S448
Identified Species:
42.5
UniProt:
Q9ULE0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULE0
NP_056506.2
1092
122676
S448
R
S
L
D
T
P
Q
S
L
A
S
L
S
S
R
Chimpanzee
Pan troglodytes
XP_527107
1298
144791
L697
K
A
E
G
G
G
R
L
Q
A
L
R
S
L
S
Rhesus Macaque
Macaca mulatta
XP_001092580
1192
133400
L522
S
Q
P
G
Q
S
G
L
C
G
V
A
A
A
A
Dog
Lupus familis
XP_548855
1157
130076
S516
R
S
L
D
T
P
Q
S
L
A
S
L
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5SXA9
1104
124092
K511
D
E
V
A
K
T
Q
K
A
E
G
G
S
R
L
Rat
Rattus norvegicus
XP_001069576
1170
133417
S528
K
S
L
D
T
P
Q
S
L
A
S
L
S
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416846
1237
140450
S596
R
S
L
D
T
P
Q
S
L
A
S
L
S
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103940
1148
130310
S524
L
T
S
L
S
S
R
S
S
L
S
S
L
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396884
1278
142650
L515
S
L
S
P
R
S
S
L
S
S
V
S
P
P
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.5
39.9
80.3
N.A.
40.7
79.2
N.A.
N.A.
70.9
N.A.
54
N.A.
N.A.
29.4
N.A.
N.A.
Protein Similarity:
100
40.4
56.8
85.3
N.A.
58.4
83.8
N.A.
N.A.
77.1
N.A.
66.6
N.A.
N.A.
46.4
N.A.
N.A.
P-Site Identity:
100
13.3
0
100
N.A.
13.3
93.3
N.A.
N.A.
100
N.A.
20
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
33.3
13.3
100
N.A.
20
100
N.A.
N.A.
100
N.A.
40
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
12
0
0
0
0
12
56
0
12
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
12
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
12
0
0
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
23
12
12
12
0
0
12
12
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
23
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
12
12
45
12
0
0
0
34
45
12
12
45
12
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
12
0
45
0
0
0
0
0
0
12
12
12
% P
% Gln:
0
12
0
0
12
0
56
0
12
0
0
0
0
0
0
% Q
% Arg:
34
0
0
0
12
0
23
0
0
0
0
12
0
12
45
% R
% Ser:
23
45
23
0
12
34
12
56
23
12
56
23
67
56
12
% S
% Thr:
0
12
0
0
45
12
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
23
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _