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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND2A
All Species:
24.55
Human Site:
S310
Identified Species:
77.14
UniProt:
Q9ULE3
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULE3
NP_056504.3
1009
113893
S310
P
P
P
P
L
P
S
S
P
P
P
S
S
V
N
Chimpanzee
Pan troglodytes
XP_001154173
1009
113820
S310
P
P
P
P
L
P
S
S
P
P
P
S
S
V
N
Rhesus Macaque
Macaca mulatta
XP_001107787
1160
129661
S345
L
P
K
P
G
S
P
S
T
P
M
T
L
L
L
Dog
Lupus familis
XP_539882
1155
129381
S440
P
P
P
P
L
P
S
S
P
P
P
S
S
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4S8
1000
113076
S303
P
P
P
P
L
P
S
S
P
P
P
T
S
V
N
Rat
Rattus norvegicus
XP_231654
998
112818
S301
P
P
P
P
L
P
S
S
P
P
P
T
S
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507742
942
107973
E284
K
R
K
S
F
E
F
E
D
I
Q
H
F
R
N
Chicken
Gallus gallus
XP_416349
1109
125060
S406
P
P
P
P
L
P
S
S
P
P
P
S
A
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
75.5
76
N.A.
81.8
81.8
N.A.
44
67.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
78
80.5
N.A.
87.2
87.7
N.A.
58.9
75.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
100
N.A.
93.3
93.3
N.A.
6.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
6.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
13
0
13
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
13
0
13
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
13
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
0
0
0
75
0
0
0
0
0
0
0
13
13
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% N
% Pro:
75
88
75
88
0
75
13
0
75
88
75
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% Q
% Arg:
0
13
0
0
0
0
0
0
0
0
0
0
0
13
0
% R
% Ser:
0
0
0
13
0
13
75
88
0
0
0
50
63
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
13
0
0
38
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _