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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80 All Species: 22.73
Human Site: S1536 Identified Species: 41.67
UniProt: Q9ULG1 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULG1 NP_060023.1 1556 176753 S1536 K N L H M T S S L A P D S L V
Chimpanzee Pan troglodytes XP_510320 1556 176707 S1536 K N L H M T S S L A P D S L V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849183 1560 177030 S1540 K S L H L T S S L A P D S L V
Cat Felis silvestris
Mouse Mus musculus Q6ZPV2 1559 176501 S1539 K S L H M T S S L A S D S L I
Rat Rattus norvegicus XP_001080838 1559 176626 S1539 K S L H M T S S L A S D P L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421134 1560 177355 S1540 K S L N L T S S L V S E T A I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038584 1552 176184 S1533 Q T L A H G S S Q S Q H N P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDY1 1638 187067 G1588 T A T P I S R G T R G A P R A
Honey Bee Apis mellifera XP_393832 1580 181173 P1561 S S G S E S R P F G F Y T Q Q
Nematode Worm Caenorhab. elegans Q9NEL2 2395 268708 I1897 V T M S D E S I V A Y E A S K
Sea Urchin Strong. purpuratus XP_795650 1571 179001 K1550 D D M Y E K H K G L W R F T M
Poplar Tree Populus trichocarpa XP_002323271 1540 175822 A1516 K L E P A F T A T P S I D S S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXS6 1507 172153 P1487 S I N E S L E P V F S A S V T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 98.3 N.A. 96.9 97 N.A. N.A. 90.6 N.A. 75 N.A. 42.3 47.4 20.2 49.7
Protein Similarity: 100 100 N.A. 99 N.A. 98.2 98.4 N.A. N.A. 95.3 N.A. 85.3 N.A. 56.6 62 34.3 65.5
P-Site Identity: 100 100 N.A. 86.6 N.A. 80 73.3 N.A. N.A. 40 N.A. 20 N.A. 0 0 13.3 0
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 86.6 N.A. N.A. 80 N.A. 40 N.A. 13.3 20 40 26.6
Percent
Protein Identity: 36.2 N.A. N.A. 29.3 N.A. N.A.
Protein Similarity: 54 N.A. N.A. 47.1 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 0 8 0 47 0 16 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 8 0 0 0 0 0 0 39 8 0 0 % D
% Glu: 0 0 8 8 16 8 8 0 0 0 0 16 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 8 8 8 0 8 0 0 % F
% Gly: 0 0 8 0 0 8 0 8 8 8 8 0 0 0 0 % G
% His: 0 0 0 39 8 0 8 0 0 0 0 8 0 0 0 % H
% Ile: 0 8 0 0 8 0 0 8 0 0 0 8 0 0 24 % I
% Lys: 54 0 0 0 0 8 0 8 0 0 0 0 0 0 8 % K
% Leu: 0 8 54 0 16 8 0 0 47 8 0 0 0 39 0 % L
% Met: 0 0 16 0 31 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 16 8 8 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 16 0 0 0 16 0 8 24 0 16 8 0 % P
% Gln: 8 0 0 0 0 0 0 0 8 0 8 0 0 8 8 % Q
% Arg: 0 0 0 0 0 0 16 0 0 8 0 8 0 8 0 % R
% Ser: 16 39 0 16 8 16 62 54 0 8 39 0 39 16 8 % S
% Thr: 8 16 8 0 0 47 8 0 16 0 0 0 16 8 16 % T
% Val: 8 0 0 0 0 0 0 0 16 8 0 0 0 8 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _