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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80 All Species: 24.24
Human Site: S421 Identified Species: 44.44
UniProt: Q9ULG1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULG1 NP_060023.1 1556 176753 S421 I L R K L E D S S T Q R Q I D
Chimpanzee Pan troglodytes XP_510320 1556 176707 S421 I L R K L E D S S T Q R Q I D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849183 1560 177030 S424 I L R K L E D S S T Q R Q I D
Cat Felis silvestris
Mouse Mus musculus Q6ZPV2 1559 176501 S423 I L R K L E D S S T Q R Q I D
Rat Rattus norvegicus XP_001080838 1559 176626 S423 I L R K L E D S S T Q R Q I D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421134 1560 177355 S422 I L R K L E D S S T Q R Q I D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038584 1552 176184 N411 I L R K L E D N S S Q R Q I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDY1 1638 187067 Q438 F M S K K L G Q G S E E D Q L
Honey Bee Apis mellifera XP_393832 1580 181173 L357 P E E Q L R I L N Q L D E E K
Nematode Worm Caenorhab. elegans Q9NEL2 2395 268708 E461 E A C G D N E E K M E I D E S
Sea Urchin Strong. purpuratus XP_795650 1571 179001 M413 E R N R I L N M L D E K T P K
Poplar Tree Populus trichocarpa XP_002323271 1540 175822 A379 H R K Q L I D A K R F S E N C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXS6 1507 172153 T401 R S Y K I P R T A P I R T R K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 98.3 N.A. 96.9 97 N.A. N.A. 90.6 N.A. 75 N.A. 42.3 47.4 20.2 49.7
Protein Similarity: 100 100 N.A. 99 N.A. 98.2 98.4 N.A. N.A. 95.3 N.A. 85.3 N.A. 56.6 62 34.3 65.5
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 86.6 N.A. 6.6 6.6 0 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 26.6 26.6 13.3 33.3
Percent
Protein Identity: 36.2 N.A. N.A. 29.3 N.A. N.A.
Protein Similarity: 54 N.A. N.A. 47.1 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 8 8 0 0 0 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 8 0 62 0 0 8 0 8 16 0 54 % D
% Glu: 16 8 8 0 0 54 8 8 0 0 24 8 16 16 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 8 0 8 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 54 0 0 0 16 8 8 0 0 0 8 8 0 54 0 % I
% Lys: 0 0 8 70 8 0 0 0 16 0 0 8 0 0 24 % K
% Leu: 0 54 0 0 70 16 0 8 8 0 8 0 0 0 8 % L
% Met: 0 8 0 0 0 0 0 8 0 8 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 8 8 8 0 0 0 0 8 0 % N
% Pro: 8 0 0 0 0 8 0 0 0 8 0 0 0 8 0 % P
% Gln: 0 0 0 16 0 0 0 8 0 8 54 0 54 8 0 % Q
% Arg: 8 16 54 8 0 8 8 0 0 8 0 62 0 8 0 % R
% Ser: 0 8 8 0 0 0 0 47 54 16 0 8 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 8 0 47 0 0 16 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _