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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80 All Species: 6.97
Human Site: S865 Identified Species: 12.78
UniProt: Q9ULG1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULG1 NP_060023.1 1556 176753 S865 D R W L R V L S P F A P D Y I
Chimpanzee Pan troglodytes XP_510320 1556 176707 S865 D R W L R V L S P F A P D Y I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849183 1560 177030 L868 D R W L R V L L S P F A P D Y
Cat Felis silvestris
Mouse Mus musculus Q6ZPV2 1559 176501 L867 D R W L K V L L S P F A P D Y
Rat Rattus norvegicus XP_001080838 1559 176626 L867 D R W L K V L L S P F A P D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421134 1560 177355 L866 D R W L R V L L S P F A P D H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038584 1552 176184 S856 K L K Q T L L S P F S A Q H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDY1 1638 187067 N884 H L L Y N R F N I F K S E Y I
Honey Bee Apis mellifera XP_393832 1580 181173 L781 D H L L Y N K L F I F A T E Y
Nematode Worm Caenorhab. elegans Q9NEL2 2395 268708 E923 Y P E P R A P E V G G F R F N
Sea Urchin Strong. purpuratus XP_795650 1571 179001 I857 V L Y H M L S I F T A E N I H
Poplar Tree Populus trichocarpa XP_002323271 1540 175822 H845 R K T E V T V H C K L S S R Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXS6 1507 172153 H832 T K T E V T V H C K L S S R Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 98.3 N.A. 96.9 97 N.A. N.A. 90.6 N.A. 75 N.A. 42.3 47.4 20.2 49.7
Protein Similarity: 100 100 N.A. 99 N.A. 98.2 98.4 N.A. N.A. 95.3 N.A. 85.3 N.A. 56.6 62 34.3 65.5
P-Site Identity: 100 100 N.A. 46.6 N.A. 40 40 N.A. N.A. 46.6 N.A. 33.3 N.A. 20 13.3 6.6 6.6
P-Site Similarity: 100 100 N.A. 46.6 N.A. 46.6 46.6 N.A. N.A. 46.6 N.A. 53.3 N.A. 33.3 13.3 13.3 26.6
Percent
Protein Identity: 36.2 N.A. N.A. 29.3 N.A. N.A.
Protein Similarity: 54 N.A. N.A. 47.1 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 24 47 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % C
% Asp: 54 0 0 0 0 0 0 0 0 0 0 0 16 31 0 % D
% Glu: 0 0 8 16 0 0 0 8 0 0 0 8 8 8 0 % E
% Phe: 0 0 0 0 0 0 8 0 16 31 39 8 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % G
% His: 8 8 0 8 0 0 0 16 0 0 0 0 0 8 16 % H
% Ile: 0 0 0 0 0 0 0 8 8 8 0 0 0 8 31 % I
% Lys: 8 16 8 0 16 0 8 0 0 16 8 0 0 0 0 % K
% Leu: 0 24 16 54 0 16 54 39 0 0 16 0 0 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 0 8 0 0 0 0 8 0 8 % N
% Pro: 0 8 0 8 0 0 8 0 24 31 0 16 31 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 16 % Q
% Arg: 8 47 0 0 39 8 0 0 0 0 0 0 8 16 0 % R
% Ser: 0 0 0 0 0 0 8 24 31 0 8 24 16 0 0 % S
% Thr: 8 0 16 0 8 16 0 0 0 8 0 0 8 0 0 % T
% Val: 8 0 0 0 16 47 16 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 47 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 8 8 0 0 0 0 0 0 0 0 24 31 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _