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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKL2
All Species:
12.73
Human Site:
S358
Identified Species:
40
UniProt:
Q9ULH7
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULH7
NP_054767.3
1088
118127
S358
L
N
D
K
N
S
N
S
G
N
S
A
L
N
N
Chimpanzee
Pan troglodytes
XP_001146854
1101
119613
T371
L
K
S
R
P
L
S
T
T
S
Q
S
L
N
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547119
1081
117012
T357
L
N
D
K
N
S
N
T
G
N
S
A
L
N
N
Cat
Felis silvestris
Mouse
Mus musculus
P59759
1080
117528
S359
P
I
K
T
D
K
N
S
S
S
G
S
N
S
G
Rat
Rattus norvegicus
Q8R5I7
938
101853
I269
K
L
K
Y
H
Q
Y
I
P
P
D
Q
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505409
1041
113389
T365
K
P
L
N
D
K
Q
T
S
S
G
N
S
L
S
Chicken
Gallus gallus
XP_414735
1123
122762
A396
N
G
N
T
P
L
N
A
L
N
N
N
T
P
T
Frog
Xenopus laevis
Q8AYC1
1067
117075
T353
K
S
Q
K
K
Q
N
T
I
N
T
T
I
C
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
N.A.
90
N.A.
82.5
31.1
N.A.
72.9
69
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.9
N.A.
93.1
N.A.
87.7
44.7
N.A.
79.6
78
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
N.A.
93.3
N.A.
13.3
0
N.A.
0
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
N.A.
100
N.A.
40
6.6
N.A.
26.6
33.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
13
0
0
0
25
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
25
0
25
0
0
0
0
0
13
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
0
0
0
0
25
0
25
0
0
0
13
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
0
13
13
0
0
0
13
0
0
% I
% Lys:
38
13
25
38
13
25
0
0
0
0
0
0
13
0
0
% K
% Leu:
38
13
13
0
0
25
0
0
13
0
0
0
38
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
25
13
13
25
0
63
0
0
50
13
25
13
38
50
% N
% Pro:
13
13
0
0
25
0
0
0
13
13
0
0
0
13
0
% P
% Gln:
0
0
13
0
0
25
13
0
0
0
13
13
0
0
0
% Q
% Arg:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
13
13
0
0
25
13
25
25
38
25
25
13
13
13
% S
% Thr:
0
0
0
25
0
0
0
50
13
0
13
13
13
0
13
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _