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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED23
All Species:
10.61
Human Site:
S1357
Identified Species:
21.21
UniProt:
Q9ULK4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULK4
NP_004821.2
1368
156474
S1357
S
G
S
P
A
P
Q
S
N
Q
V
P
V
S
L
Chimpanzee
Pan troglodytes
XP_527503
1501
171042
N1491
A
V
P
P
Q
A
M
N
S
G
S
P
A
P
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532052
1371
156744
S1360
S
G
S
P
A
P
Q
S
N
Q
V
P
V
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80YQ2
1367
156069
S1356
S
G
S
P
A
P
Q
S
N
Q
V
P
A
S
L
Rat
Rattus norvegicus
Q5EB59
1367
156213
A1356
S
G
S
P
A
P
Q
A
N
Q
V
P
T
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505931
1334
152781
P1321
S
G
S
P
A
P
Q
P
S
Q
V
P
V
N
V
Chicken
Gallus gallus
XP_424537
1446
165201
A1433
N
G
S
P
A
Q
Q
A
S
Q
V
P
V
N
V
Frog
Xenopus laevis
Q6P423
1369
156554
P1356
S
G
S
P
A
P
Q
P
N
Q
V
P
V
S
V
Zebra Danio
Brachydanio rerio
Q5RIW8
1376
156864
A1357
S
V
Q
Q
T
S
S
A
S
S
P
T
A
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1X7
1439
167047
Q1349
S
N
N
A
I
T
S
Q
T
Q
S
P
M
Q
T
Honey Bee
Apis mellifera
XP_395793
1355
154984
A1345
Q
M
R
L
R
F
I
A
H
I
N
I
D
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799077
1150
132126
S1140
V
E
S
L
A
V
S
S
R
P
A
P
Y
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.5
N.A.
98.3
N.A.
96.2
96.6
N.A.
92.7
90.3
92.9
90.6
N.A.
46.7
59.5
N.A.
46.7
Protein Similarity:
100
90.5
N.A.
99.3
N.A.
98.4
98.7
N.A.
95.2
92.5
96.9
95.1
N.A.
65.8
74.4
N.A.
62.4
P-Site Identity:
100
13.3
N.A.
100
N.A.
93.3
80
N.A.
73.3
60
86.6
6.6
N.A.
20
0
N.A.
33.3
P-Site Similarity:
100
33.3
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
20
N.A.
33.3
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
67
9
0
34
0
0
9
0
25
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
59
0
0
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
0
9
0
9
0
0
17
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
34
% L
% Met:
0
9
0
0
0
0
9
0
0
0
0
0
9
0
0
% M
% Asn:
9
9
9
0
0
0
0
9
42
0
9
0
0
17
0
% N
% Pro:
0
0
9
67
0
50
0
17
0
9
9
84
0
9
0
% P
% Gln:
9
0
9
9
9
9
59
9
0
67
0
0
0
17
9
% Q
% Arg:
0
0
9
0
9
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
67
0
67
0
0
9
25
34
34
9
17
0
0
42
9
% S
% Thr:
0
0
0
0
9
9
0
0
9
0
0
9
9
0
9
% T
% Val:
9
17
0
0
0
9
0
0
0
0
59
0
42
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _