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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED23
All Species:
21.82
Human Site:
T1333
Identified Species:
43.64
UniProt:
Q9ULK4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULK4
NP_004821.2
1368
156474
T1333
K
L
R
L
R
F
I
T
H
I
S
K
M
E
P
Chimpanzee
Pan troglodytes
XP_527503
1501
171042
L1467
I
C
N
L
K
P
A
L
K
L
R
L
R
F
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532052
1371
156744
T1336
K
L
R
L
R
F
I
T
H
I
S
K
M
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80YQ2
1367
156069
I1332
L
K
L
R
L
R
F
I
T
H
I
S
K
M
E
Rat
Rattus norvegicus
Q5EB59
1367
156213
I1332
L
K
L
R
L
R
F
I
T
H
I
S
K
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505931
1334
152781
T1297
K
L
R
L
R
F
I
T
H
I
S
K
M
E
P
Chicken
Gallus gallus
XP_424537
1446
165201
T1409
K
L
R
L
R
F
I
T
H
I
S
K
M
E
P
Frog
Xenopus laevis
Q6P423
1369
156554
I1332
L
K
L
R
L
R
H
I
T
H
I
S
T
E
S
Zebra Danio
Brachydanio rerio
Q5RIW8
1376
156864
T1333
R
L
R
L
R
F
I
T
H
I
S
K
M
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1X7
1439
167047
T1325
Q
M
R
L
R
F
I
T
H
L
N
L
E
D
I
Honey Bee
Apis mellifera
XP_395793
1355
154984
M1321
K
Y
M
F
V
G
D
M
T
K
N
E
V
E
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799077
1150
132126
R1116
A
D
A
E
K
V
I
R
G
L
K
P
P
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.5
N.A.
98.3
N.A.
96.2
96.6
N.A.
92.7
90.3
92.9
90.6
N.A.
46.7
59.5
N.A.
46.7
Protein Similarity:
100
90.5
N.A.
99.3
N.A.
98.4
98.7
N.A.
95.2
92.5
96.9
95.1
N.A.
65.8
74.4
N.A.
62.4
P-Site Identity:
100
6.6
N.A.
100
N.A.
0
0
N.A.
100
100
6.6
93.3
N.A.
46.6
13.3
N.A.
6.6
P-Site Similarity:
100
20
N.A.
100
N.A.
0
0
N.A.
100
100
6.6
100
N.A.
80
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
0
9
9
59
17
% E
% Phe:
0
0
0
9
0
50
17
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
50
25
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
59
25
0
42
25
0
0
0
17
% I
% Lys:
42
25
0
0
17
0
0
0
9
9
9
42
17
0
0
% K
% Leu:
25
42
25
59
25
0
0
9
0
25
0
17
0
9
0
% L
% Met:
0
9
9
0
0
0
0
9
0
0
0
0
42
17
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
9
9
0
42
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
50
25
50
25
0
9
0
0
9
0
9
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
42
25
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
50
34
0
0
0
9
0
0
% T
% Val:
0
0
0
0
9
9
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _