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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED23 All Species: 21.82
Human Site: T1333 Identified Species: 43.64
UniProt: Q9ULK4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULK4 NP_004821.2 1368 156474 T1333 K L R L R F I T H I S K M E P
Chimpanzee Pan troglodytes XP_527503 1501 171042 L1467 I C N L K P A L K L R L R F I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532052 1371 156744 T1336 K L R L R F I T H I S K M E P
Cat Felis silvestris
Mouse Mus musculus Q80YQ2 1367 156069 I1332 L K L R L R F I T H I S K M E
Rat Rattus norvegicus Q5EB59 1367 156213 I1332 L K L R L R F I T H I S K M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505931 1334 152781 T1297 K L R L R F I T H I S K M E P
Chicken Gallus gallus XP_424537 1446 165201 T1409 K L R L R F I T H I S K M E P
Frog Xenopus laevis Q6P423 1369 156554 I1332 L K L R L R H I T H I S T E S
Zebra Danio Brachydanio rerio Q5RIW8 1376 156864 T1333 R L R L R F I T H I S K M E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1X7 1439 167047 T1325 Q M R L R F I T H L N L E D I
Honey Bee Apis mellifera XP_395793 1355 154984 M1321 K Y M F V G D M T K N E V E C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799077 1150 132126 R1116 A D A E K V I R G L K P P L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.5 N.A. 98.3 N.A. 96.2 96.6 N.A. 92.7 90.3 92.9 90.6 N.A. 46.7 59.5 N.A. 46.7
Protein Similarity: 100 90.5 N.A. 99.3 N.A. 98.4 98.7 N.A. 95.2 92.5 96.9 95.1 N.A. 65.8 74.4 N.A. 62.4
P-Site Identity: 100 6.6 N.A. 100 N.A. 0 0 N.A. 100 100 6.6 93.3 N.A. 46.6 13.3 N.A. 6.6
P-Site Similarity: 100 20 N.A. 100 N.A. 0 0 N.A. 100 100 6.6 100 N.A. 80 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 9 0 0 0 0 9 0 0 0 0 0 0 9 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 0 9 9 59 17 % E
% Phe: 0 0 0 9 0 50 17 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 50 25 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 59 25 0 42 25 0 0 0 17 % I
% Lys: 42 25 0 0 17 0 0 0 9 9 9 42 17 0 0 % K
% Leu: 25 42 25 59 25 0 0 9 0 25 0 17 0 9 0 % L
% Met: 0 9 9 0 0 0 0 9 0 0 0 0 42 17 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 17 0 0 0 0 % N
% Pro: 0 0 0 0 0 9 0 0 0 0 0 9 9 0 42 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 50 25 50 25 0 9 0 0 9 0 9 0 9 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 42 25 0 0 9 % S
% Thr: 0 0 0 0 0 0 0 50 34 0 0 0 9 0 0 % T
% Val: 0 0 0 0 9 9 0 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _