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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED23 All Species: 34.55
Human Site: T698 Identified Species: 69.09
UniProt: Q9ULK4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULK4 NP_004821.2 1368 156474 T698 L A R A T H V T D F F T G S D
Chimpanzee Pan troglodytes XP_527503 1501 171042 T840 L A R A T H V T D F F T G S D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532052 1371 156744 T701 L A R A T H V T D F F T G S D
Cat Felis silvestris
Mouse Mus musculus Q80YQ2 1367 156069 T698 L A R A T H V T D F F T G S D
Rat Rattus norvegicus Q5EB59 1367 156213 T698 L A R A T H V T D F F T G S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505931 1334 152781 F664 R A T H V T D F F T G S D S I
Chicken Gallus gallus XP_424537 1446 165201 T774 L A R A T H V T D F F T G S D
Frog Xenopus laevis Q6P423 1369 156554 T698 I A R A T H V T D F F T G S E
Zebra Danio Brachydanio rerio Q5RIW8 1376 156864 T698 L A R A T H V T D F F T G S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1X7 1439 167047 H701 L T L A R S M H V H G G G D E
Honey Bee Apis mellifera XP_395793 1355 154984 T714 L A R S M H V T G T G S D S H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799077 1150 132126 F534 P S A L Q S F F E Q H N M P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.5 N.A. 98.3 N.A. 96.2 96.6 N.A. 92.7 90.3 92.9 90.6 N.A. 46.7 59.5 N.A. 46.7
Protein Similarity: 100 90.5 N.A. 99.3 N.A. 98.4 98.7 N.A. 95.2 92.5 96.9 95.1 N.A. 65.8 74.4 N.A. 62.4
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 13.3 100 86.6 100 N.A. 20 46.6 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 20 100 100 100 N.A. 33.3 60 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 84 9 75 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 67 0 0 0 17 9 59 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 17 % E
% Phe: 0 0 0 0 0 0 9 17 9 67 67 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 0 25 9 75 0 0 % G
% His: 0 0 0 9 0 75 0 9 0 9 9 0 0 0 9 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 75 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 9 0 9 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 9 0 75 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 9 0 17 0 0 0 0 0 17 0 84 0 % S
% Thr: 0 9 9 0 67 9 0 75 0 17 0 67 0 0 9 % T
% Val: 0 0 0 0 9 0 75 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _