KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF150
All Species:
13.33
Human Site:
S408
Identified Species:
29.33
UniProt:
Q9ULK6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULK6
NP_065775.1
438
48072
S408
E
Q
E
P
A
V
S
S
D
S
D
I
S
L
I
Chimpanzee
Pan troglodytes
XP_001143540
558
60027
I527
A
V
T
K
E
W
F
I
I
A
S
F
G
L
L
Rhesus Macaque
Macaca mulatta
XP_001106945
400
42977
C371
P
A
E
S
E
P
Q
C
D
A
S
F
K
G
D
Dog
Lupus familis
XP_849454
855
91833
S825
E
P
E
P
A
V
S
S
D
S
D
I
S
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5DTZ6
437
47994
S407
G
Q
E
P
A
L
S
S
D
S
D
I
S
L
I
Rat
Rattus norvegicus
Q6Y290
419
46430
K384
E
I
N
I
A
V
T
K
E
W
F
I
I
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512762
290
32407
D261
Q
E
P
A
V
S
S
D
S
D
I
S
L
I
M
Chicken
Gallus gallus
Q90972
381
42801
S352
D
N
D
N
I
D
S
S
D
A
E
S
G
V
N
Frog
Xenopus laevis
Q6NRX0
397
43453
S368
S
S
L
Q
Q
S
N
S
V
K
D
D
A
G
E
Zebra Danio
Brachydanio rerio
Q566M8
419
46332
S387
D
T
M
P
T
E
Q
S
E
L
Q
P
I
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06003
461
52604
R432
S
L
S
L
R
Q
A
R
D
W
V
S
L
M
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.3
37.2
45.5
N.A.
94.2
47.4
N.A.
52.9
23.5
35.1
68
N.A.
32.3
N.A.
N.A.
N.A.
Protein Similarity:
100
52.3
56.3
48.6
N.A.
95.8
62.5
N.A.
58.2
42.4
54.5
79
N.A.
50.9
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
93.3
N.A.
86.6
26.6
N.A.
6.6
20
13.3
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
93.3
N.A.
93.3
40
N.A.
33.3
53.3
26.6
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
37
0
10
0
0
28
0
0
10
19
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
19
0
10
0
0
10
0
10
55
10
37
10
0
0
10
% D
% Glu:
28
10
37
0
19
10
0
0
19
0
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
10
19
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
19
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
10
0
0
10
10
0
10
37
19
10
28
% I
% Lys:
0
0
0
10
0
0
0
10
0
10
0
0
10
0
0
% K
% Leu:
0
10
10
10
0
10
0
0
0
10
0
0
19
37
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
10
10
10
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
10
10
10
37
0
10
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
19
0
10
10
10
19
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
19
10
10
10
0
19
46
55
10
28
19
28
28
0
28
% S
% Thr:
0
10
10
0
10
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
10
28
0
0
10
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
19
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _