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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEKHG1 All Species: 21.82
Human Site: S1185 Identified Species: 60
UniProt: Q9ULL1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULL1 NP_001025055.1 1385 155439 S1185 Y H R S Q S S S S V L I N K S
Chimpanzee Pan troglodytes XP_001135904 1385 155562 S1185 Y H R S Q S S S S V L I N K S
Rhesus Macaque Macaca mulatta XP_001098617 1385 155017 S1185 Y H R S Q S S S S V L I N K S
Dog Lupus familis XP_541152 1592 176995 S1392 Y S R S Q S S S S I L I N K S
Cat Felis silvestris
Mouse Mus musculus Q4VAC9 1341 148554 V1140 F S F S P S A V S P R T T S P
Rat Rattus norvegicus XP_001054556 1380 155100 P1182 K L Q P Y S R P Q S S S S V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505870 1468 165754 S1266 Y S R S Q S S S S V V V N K S
Chicken Gallus gallus XP_419671 1405 159118 S1203 Y S R S Q S S S S I V V N R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684692 1266 140285 P1070 R W S A C V T P S K D D S E H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 92 74.3 N.A. 28.3 79.9 N.A. 67.7 66.3 N.A. 23.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 93 79.2 N.A. 44.4 86.7 N.A. 77.3 76.5 N.A. 41.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 20 6.6 N.A. 80 66.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 33.3 20 N.A. 93.3 93.3 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 12 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % E
% Phe: 12 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 0 0 0 0 0 0 0 0 0 23 0 45 0 0 0 % I
% Lys: 12 0 0 0 0 0 0 0 0 12 0 0 0 56 0 % K
% Leu: 0 12 0 0 0 0 0 0 0 0 45 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % N
% Pro: 0 0 0 12 12 0 0 23 0 12 0 0 0 0 12 % P
% Gln: 0 0 12 0 67 0 0 0 12 0 0 0 0 0 0 % Q
% Arg: 12 0 67 0 0 0 12 0 0 0 12 0 0 12 0 % R
% Ser: 0 45 12 78 0 89 67 67 89 12 12 12 23 12 67 % S
% Thr: 0 0 0 0 0 0 12 0 0 0 0 12 12 0 0 % T
% Val: 0 0 0 0 0 12 0 12 0 45 23 23 0 12 0 % V
% Trp: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 67 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _