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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHROOM4
All Species:
4.24
Human Site:
S452
Identified Species:
11.67
UniProt:
Q9ULL8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULL8
NP_065768.2
1498
165499
S452
W
T
L
S
P
L
H
S
S
H
K
G
K
K
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083331
1400
154301
P448
K
G
K
K
S
P
C
P
P
A
G
G
T
H
D
Dog
Lupus familis
XP_855411
1714
187976
S682
W
T
L
S
P
L
H
S
S
H
T
G
K
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q1W617
1475
163220
N453
W
T
V
S
P
L
H
N
N
P
K
G
K
K
S
Rat
Rattus norvegicus
Q7TP36
1423
157971
R451
P
R
A
S
H
T
V
R
A
G
L
Q
C
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514972
1675
186527
Q523
R
T
K
Y
S
L
P
Q
N
C
E
L
V
D
I
Chicken
Gallus gallus
XP_416847
1669
186299
A567
E
A
K
K
T
N
H
A
E
K
S
G
Q
K
K
Frog
Xenopus laevis
Q27IV2
1788
200696
K523
E
S
P
S
P
S
Q
K
K
S
Y
D
F
T
R
Zebra Danio
Brachydanio rerio
XP_002662506
1695
189259
L550
A
A
S
L
S
V
N
L
G
V
N
S
H
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
79.3
74
N.A.
77.7
22.8
N.A.
23.8
24.6
20.8
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
82.4
77.8
N.A.
84.7
36.7
N.A.
40
40
37.7
38.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
73.3
6.6
N.A.
13.3
20
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
6.6
93.3
N.A.
93.3
13.3
N.A.
26.6
33.3
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
12
0
0
0
0
12
12
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
12
0
0
12
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
12
% D
% Glu:
23
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
12
12
12
56
0
0
12
% G
% His:
0
0
0
0
12
0
45
0
0
23
0
0
12
23
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% I
% Lys:
12
0
34
23
0
0
0
12
12
12
23
0
34
45
12
% K
% Leu:
0
0
23
12
0
45
0
12
0
0
12
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
12
12
23
0
12
0
0
0
0
% N
% Pro:
12
0
12
0
45
12
12
12
12
12
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
12
12
0
0
0
12
12
0
0
% Q
% Arg:
12
12
0
0
0
0
0
12
0
0
0
0
0
0
12
% R
% Ser:
0
12
12
56
34
12
0
23
23
12
12
12
0
0
34
% S
% Thr:
0
45
0
0
12
12
0
0
0
0
12
0
12
12
0
% T
% Val:
0
0
12
0
0
12
12
0
0
12
0
0
12
0
0
% V
% Trp:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _