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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHH1
All Species:
0.61
Human Site:
S242
Identified Species:
1.67
UniProt:
Q9ULM0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULM0
NP_065766.1
1364
151232
S242
P
L
E
D
S
S
S
S
T
V
H
S
G
E
T
Chimpanzee
Pan troglodytes
XP_525888
1493
168136
Q241
P
E
K
S
V
D
N
Q
V
L
E
N
N
R
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537487
1476
163215
I355
S
L
E
D
S
S
P
I
V
V
H
P
G
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80TI1
1356
150890
M241
L
E
D
L
R
F
S
M
V
H
P
G
E
T
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516496
937
103987
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q00IB7
1433
160027
K248
L
L
P
M
L
Q
D
K
A
D
S
P
K
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5D0
1820
198623
V508
Q
E
L
E
R
N
L
V
A
A
V
D
G
L
T
Honey Bee
Apis mellifera
XP_001120273
1571
174100
S287
S
K
S
F
D
G
Y
S
S
A
V
E
E
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782886
2057
229359
L333
D
L
D
H
S
M
S
L
L
S
T
S
S
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
80.5
N.A.
83.5
N.A.
N.A.
43.1
N.A.
N.A.
56.7
N.A.
30.7
35.6
N.A.
30.7
Protein Similarity:
100
65.5
N.A.
84.1
N.A.
88.8
N.A.
N.A.
54.1
N.A.
N.A.
71.8
N.A.
46.4
51.5
N.A.
43.4
P-Site Identity:
100
6.6
N.A.
60
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
6.6
N.A.
13.3
6.6
N.A.
26.6
P-Site Similarity:
100
33.3
N.A.
60
N.A.
13.3
N.A.
N.A.
0
N.A.
N.A.
13.3
N.A.
26.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
23
23
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
23
23
12
12
12
0
0
12
0
12
0
0
0
% D
% Glu:
0
34
23
12
0
0
0
0
0
0
12
12
23
23
0
% E
% Phe:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
12
34
12
23
% G
% His:
0
0
0
12
0
0
0
0
0
12
23
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% I
% Lys:
0
12
12
0
0
0
0
12
0
0
0
0
12
0
0
% K
% Leu:
23
45
12
12
12
0
12
12
12
12
0
0
0
23
0
% L
% Met:
0
0
0
12
0
12
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
12
0
0
0
0
12
12
0
12
% N
% Pro:
23
0
12
0
0
0
12
0
0
0
12
23
0
0
0
% P
% Gln:
12
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
23
0
0
0
0
0
0
0
0
12
0
% R
% Ser:
23
0
12
12
34
23
34
23
12
12
12
23
12
12
12
% S
% Thr:
0
0
0
0
0
0
0
0
12
0
12
0
0
12
23
% T
% Val:
0
0
0
0
12
0
0
12
34
23
23
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _