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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHH1
All Species:
0
Human Site:
T274
Identified Species:
0
UniProt:
Q9ULM0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULM0
NP_065766.1
1364
151232
T274
Q
P
C
M
K
L
L
T
F
R
C
S
S
A
S
Chimpanzee
Pan troglodytes
XP_525888
1493
168136
G273
R
T
S
F
A
T
D
G
G
I
S
Q
N
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537487
1476
163215
H387
L
C
M
K
P
R
T
H
R
H
G
S
A
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q80TI1
1356
150890
P273
L
C
M
K
P
G
N
P
K
H
G
S
A
S
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516496
937
103987
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q00IB7
1433
160027
R280
E
P
S
F
G
V
M
R
D
R
A
M
G
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5D0
1820
198623
P540
E
S
G
V
V
T
R
P
D
S
S
D
T
D
T
Honey Bee
Apis mellifera
XP_001120273
1571
174100
M319
Q
A
T
R
V
R
D
M
L
R
E
K
V
R
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782886
2057
229359
A365
T
P
G
G
D
G
G
A
N
L
A
Q
S
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
80.5
N.A.
83.5
N.A.
N.A.
43.1
N.A.
N.A.
56.7
N.A.
30.7
35.6
N.A.
30.7
Protein Similarity:
100
65.5
N.A.
84.1
N.A.
88.8
N.A.
N.A.
54.1
N.A.
N.A.
71.8
N.A.
46.4
51.5
N.A.
43.4
P-Site Identity:
100
0
N.A.
6.6
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
13.3
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
20
N.A.
20
N.A.
20
N.A.
N.A.
0
N.A.
N.A.
40
N.A.
26.6
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
12
0
0
12
0
0
23
0
23
12
12
% A
% Cys:
0
23
12
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
23
0
23
0
0
12
0
12
0
% D
% Glu:
23
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
23
0
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
0
23
12
12
23
12
12
12
0
23
0
12
12
12
% G
% His:
0
0
0
0
0
0
0
12
0
23
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
23
12
0
0
0
12
0
0
12
0
0
0
% K
% Leu:
23
0
0
0
0
12
12
0
12
12
0
0
0
12
0
% L
% Met:
0
0
23
12
0
0
12
12
0
0
0
12
0
0
23
% M
% Asn:
0
0
0
0
0
0
12
0
12
0
0
0
12
0
0
% N
% Pro:
0
34
0
0
23
0
0
23
0
0
0
0
0
0
0
% P
% Gln:
23
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% Q
% Arg:
12
0
0
12
0
23
12
12
12
34
0
0
0
12
0
% R
% Ser:
0
12
23
0
0
0
0
0
0
12
23
34
23
34
12
% S
% Thr:
12
12
12
0
0
23
12
12
0
0
0
0
12
0
12
% T
% Val:
0
0
0
12
23
12
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _