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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEKHH1 All Species: 9.09
Human Site: Y1092 Identified Species: 25
UniProt: Q9ULM0 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULM0 NP_065766.1 1364 151232 Y1092 T R V V K L M Y K N R L Y F R
Chimpanzee Pan troglodytes XP_525888 1493 168136 K1216 R T V R L T Y K N R L Y F S V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537487 1476 163215 Y1204 T R V V K L M Y K N R L Y F R
Cat Felis silvestris
Mouse Mus musculus Q80TI1 1356 150890 Y1086 T R V V K L M Y K N R L Y F R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516496 937 103987 D698 V L G L F P L D K E L A L E M
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q00IB7 1433 160027 K1156 R T V R L T Y K S R L C F R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W5D0 1820 198623 K1483 R V I Q L S Y K N R L Y W K H
Honey Bee Apis mellifera XP_001120273 1571 174100 K1297 R V I Q L T Y K S R C Y W R Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782886 2057 229359 K1343 K I I R L T Y K H K E Y Q R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49 N.A. 80.5 N.A. 83.5 N.A. N.A. 43.1 N.A. N.A. 56.7 N.A. 30.7 35.6 N.A. 30.7
Protein Similarity: 100 65.5 N.A. 84.1 N.A. 88.8 N.A. N.A. 54.1 N.A. N.A. 71.8 N.A. 46.4 51.5 N.A. 43.4
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 N.A. N.A. 6.6 N.A. N.A. 6.6 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 N.A. N.A. 20 N.A. N.A. 13.3 N.A. 13.3 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 12 12 0 0 12 0 % E
% Phe: 0 0 0 0 12 0 0 0 0 0 0 0 23 34 0 % F
% Gly: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 12 % H
% Ile: 0 12 34 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 0 0 0 34 0 0 56 45 12 0 0 0 12 0 % K
% Leu: 0 12 0 12 56 34 12 0 0 0 45 34 12 0 0 % L
% Met: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 12 % M
% Asn: 0 0 0 0 0 0 0 0 23 34 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 23 0 0 0 0 0 0 0 0 12 0 12 % Q
% Arg: 45 34 0 34 0 0 0 0 0 45 34 0 0 34 45 % R
% Ser: 0 0 0 0 0 12 0 0 23 0 0 0 0 12 0 % S
% Thr: 34 23 0 0 0 45 0 0 0 0 0 0 0 0 0 % T
% Val: 12 23 56 34 0 0 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 23 0 0 % W
% Tyr: 0 0 0 0 0 0 56 34 0 0 0 45 34 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _